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Spermine

Name: Spermine
Brand: TargetMol
SKU: T3007
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3007Cas No. 71-44-3

Alias NSC 268508, Neuridine, Musculamine, Gerontine, 4,9-Diaza-1,12-dodecanediamine

Spermine (Neuridine) is a biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.

Spermine

🥰Excellent

Purity: 99.96%

Catalog No. T3007Alias NSC 268508, Neuridine, Musculamine, Gerontine, 4,9-Diaza-1,12-dodecanediamineCas No. 71-44-3

Spermine (Neuridine) is a biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.

Pack Size	Price	Availability
50 mg	$31	In Stock
100 mg	$41	In Stock
500 mg	$92	In Stock
1 g	$133	In Stock

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Batch Information

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Purity:99.96%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Spermine (Neuridine) is a biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.
Targets&IC50	PRMT1:13.72 μM, PRMT3:42.36 μM, PRMT6:3.81 μM, PRMT4:16.63 μM, PRMT8:9.22 μM
Synonyms	NSC 268508, Neuridine, Musculamine, Gerontine, 4,9-Diaza-1,12-dodecanediamine

Chemical Properties

Molecular Weight	202.34
Formula	C₁₀H₂₆N₄
Cas No.	71-44-3
Smiles	C(CCNCCCN)CNCCCN
Relative Density.	0.925 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: Slightly soluble

H2O: 257.5 mg/mL (1272.61 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	4.9422 mL	24.7109 mL	49.4218 mL	247.1088 mL
5 mM	0.9884 mL	4.9422 mL	9.8844 mL	49.4218 mL
10 mM	0.4942 mL	2.4711 mL	4.9422 mL	24.7109 mL
20 mM	0.2471 mL	1.2355 mL	2.4711 mL	12.3554 mL
50 mM	0.0988 mL	0.4942 mL	0.9884 mL	4.9422 mL
100 mM	0.0494 mL	0.2471 mL	0.4942 mL	2.4711 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc