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2'-Deoxypseudoisocytidine

Name: 2'-Deoxypseudoisocytidine
Brand: TargetMol
SKU: T10099
Rating: 4.5 (1 reviews)

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Catalog No. T10099Cas No. 65358-18-1

2'-Deoxypseudoisocytidine, a nucleoside analogue, is characterized by its structural similarity to natural nucleosides in DNA, featuring a modified sugar moiety with a deoxygenated (2') position. It serves as a significant compound in biochemical research and medical applications for its ability to mimic the behavior of endogenous nucleosides.

2'-Deoxypseudoisocytidine

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Catalog No. T10099Cas No. 65358-18-1

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$1,670	8-10 weeks	8-10 weeks
50 mg	$2,180	8-10 weeks	8-10 weeks
100 mg	$2,800	8-10 weeks	8-10 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	2'-Deoxypseudoisocytidine, a nucleoside analogue, is characterized by its structural similarity to natural nucleosides in DNA, featuring a modified sugar moiety with a deoxygenated (2') position. It serves as a significant compound in biochemical research and medical applications for its ability to mimic the behavior of endogenous nucleosides.
In vitro	2'-Deoxypseudoisocytidine is a modified base utilized as an allele-specific blocker probe for discriminating sequence variations between alleles and quantifying rare (e.g., mutant) allelic variants [1]. Additionally, 2'-Deoxypseudoisocytidine and its analogues serve as novel base-pairing agents in oligonucleotides to study DNA and RNA structures and functions [2].

Chemical Properties

Molecular Weight	227.22
Formula	C₉H₁₃N₃O₄
Cas No.	65358-18-1
Smiles	O=C1C([C@@]2(O[C@H](CO)[C@@H](O)C2)[H])=CN=C(N)N1
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 106.5 mg/mL (468.71 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4010 mL	22.0051 mL	44.0102 mL	220.0511 mL
5 mM	0.8802 mL	4.4010 mL	8.8020 mL	44.0102 mL
10 mM	0.4401 mL	2.2005 mL	4.4010 mL	22.0051 mL
20 mM	0.2201 mL	1.1003 mL	2.2005 mL	11.0026 mL
50 mM	0.0880 mL	0.4401 mL	0.8802 mL	4.4010 mL
100 mM	0.0440 mL	0.2201 mL	0.4401 mL	2.2005 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc