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Prometryn (Synonyms: Mercazin, Gesagard, Caparol)

Catalog No. T19733 Copy Product Info
Purity: 99.74%
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Prometryn (Mercazin) is a triazine that can be used as a herbicide.

Prometryn

Copy Product Info
🥰Excellent
Catalog No. T19733
Synonyms Mercazin, Gesagard, Caparol

Prometryn (Mercazin) is a triazine that can be used as a herbicide.

Prometryn
Cas No. 7287-19-6
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Pack SizePriceUSA StockGlobal StockQuantity
25 mg$30In StockIn Stock
50 mg$48In StockIn Stock
100 mg$73In StockIn Stock
500 mg$176-In Stock
1 mL x 10 mM (in DMSO)$34In StockIn Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.74%
Appearance:Solid
Color:White
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Product Introduction

Prometryn AI Summary
Prometryn exhibits a versatile range of bioactivities. It demonstrates potency in inhibiting Polymerase Iota, human Apurinic/apyrimidinic Endonuclease 1 (APE1), and the Marburg Virus binding or entry into cells. It also antagonizes estrogen receptor alpha signaling and activates pregnane X receptor (PXR) signaling pathways in both human and rat models. Additionally, Prometryn shows robust herbicidal activity, effectively controlling glyphosate-resistant Conyza canadensis (horseweed) with residual effects ranging from 20.0% to 100.0% after treatment. It also inhibits the growth of Cyperus rotundus, Malva sylvestris, and Chenopodium murale by reducing their total dry and fresh weights, and exhibits phytotoxicity in Allium cepa (onion) seedlings. Furthermore, it significantly inhibits sodium fluorescein uptake in OATP1B1-transfected and OATP1B3-transfected CHO cells by 175.4% and 86.3% respectively, at a substrate-inhibitor concentration of 10 µM..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Prometryn (Mercazin) is a triazine that can be used as a herbicide.
SynonymsMercazin, Gesagard, Caparol
Chemical Properties
Molecular Weight241.36
FormulaC10H19N5S
Cas No.7287-19-6
SmilesCSc1nc(NC(C)C)nc(NC(C)C)n1
Relative Density.1.157
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 65 mg/mL (269.31 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.1432 mL20.7159 mL41.4319 mL207.1594 mL
5 mM0.8286 mL4.1432 mL8.2864 mL41.4319 mL
10 mM0.4143 mL2.0716 mL4.1432 mL20.7159 mL
20 mM0.2072 mL1.0358 mL2.0716 mL10.3580 mL
50 mM0.0829 mL0.4143 mL0.8286 mL4.1432 mL
100 mM0.0414 mL0.2072 mL0.4143 mL2.0716 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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