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Prometryn

Name: Prometryn
Brand: TargetMol
SKU: T19733
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19733Cas No. 7287-19-6

Alias Mercazin, Gesagard, Caparol

Prometryn (Mercazin) is a triazine that can be used as a herbicide.

Prometryn

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Purity: 99.74%

Catalog No. T19733Alias Mercazin, Gesagard, CaparolCas No. 7287-19-6

Prometryn (Mercazin) is a triazine that can be used as a herbicide.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$30	In Stock	In Stock
50 mg	$48	In Stock	In Stock
100 mg	$73	In Stock	In Stock
500 mg	$176	-	In Stock
1 mL x 10 mM (in DMSO)	$34	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.74%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Prometryn AI Summary

Prometryn exhibits a versatile range of bioactivities. It demonstrates potency in inhibiting Polymerase Iota, human Apurinic/apyrimidinic Endonuclease 1 (APE1), and the Marburg Virus binding or entry into cells. It also antagonizes estrogen receptor alpha signaling and activates pregnane X receptor (PXR) signaling pathways in both human and rat models. Additionally, Prometryn shows robust herbicidal activity, effectively controlling glyphosate-resistant Conyza canadensis (horseweed) with residual effects ranging from 20.0% to 100.0% after treatment. It also inhibits the growth of Cyperus rotundus, Malva sylvestris, and Chenopodium murale by reducing their total dry and fresh weights, and exhibits phytotoxicity in Allium cepa (onion) seedlings. Furthermore, it significantly inhibits sodium fluorescein uptake in OATP1B1-transfected and OATP1B3-transfected CHO cells by 175.4% and 86.3% respectively, at a substrate-inhibitor concentration of 10 µM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Prometryn (Mercazin) is a triazine that can be used as a herbicide.
Synonyms	Mercazin, Gesagard, Caparol

Chemical Properties

Molecular Weight	241.36
Formula	C₁₀H₁₉N₅S
Cas No.	7287-19-6
Smiles	CSc1nc(NC(C)C)nc(NC(C)C)n1
Relative Density.	1.157

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (269.31 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.1432 mL	20.7159 mL	41.4319 mL	207.1594 mL
5 mM	0.8286 mL	4.1432 mL	8.2864 mL	41.4319 mL
10 mM	0.4143 mL	2.0716 mL	4.1432 mL	20.7159 mL
20 mM	0.2072 mL	1.0358 mL	2.0716 mL	10.3580 mL
50 mM	0.0829 mL	0.4143 mL	0.8286 mL	4.1432 mL
100 mM	0.0414 mL	0.2072 mL	0.4143 mL	2.0716 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc