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Methyl β-D-Galactopyranoside

Name: Methyl β-D-Galactopyranoside
Brand: TargetMol
SKU: T4864
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4864Cas No. 1824-94-8

Alias Methyl-β-D-galactopyranoside

Methyl β-D-Galactopyranoside is an endogenous metabolite with antifungal activity.

Methyl β-D-Galactopyranoside

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Purity: 99.76%

Catalog No. T4864Alias Methyl-β-D-galactopyranosideCas No. 1824-94-8

Methyl β-D-Galactopyranoside is an endogenous metabolite with antifungal activity.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
200 mg	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock	In Stock

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Purity:99.76%

Appearance:Solid

Color:White

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COA LCMS HNMR HPLC

Product Introduction

Methyl β-D-Galactopyranoside AI Summary

Methyl β-D-Galactopyranoside exhibits diverse bioactivities and binding affinities across various targets. It shows a minimum inhibitory concentration (MIC) of 1,750,000 nM for the inhibition of flocculation against the cell wall galactose-specific yeast lectin (KbCWL) and demonstrates an inhibition constant (Ki) of 3.21 for glycogen phosphorylase b. The compound is also an inhibitor of Epstein-Barr virus antigen activation in Raji cells with efficacy increasing at higher concentrations and has a Ki value of 24,700,000 nM for glycogen phosphorylase inhibition. Additionally, it acts as an antagonist to several human galectins with varying dissociation constants (Kd): 13,000,000 nM for galectin2, 4,400,000 nM for galectin3, 6,600,000 nM for galectin4N, over 10,000,000 nM for galectin4C, 6,300,000 nM for galectin8N, and 1,200,000 nM for galectin9N. Furthermore, Methyl β-D-Galactopyranoside inhibits Pseudomonas aeruginosa PAO1 adhesion to human A549 cells with a 30% inhibition rate at concentrations of 25 to 2500 µM, and displays binding affinity to Pseudomonas aeruginosa LecA with a Kd of 70,000 nM (IC50) and another reported Kd of 55,700 nM by isothermal titration calorimetry. The compound also inhibits Escherichia coli Heptosyltransferase I, reducing ADP release by 7% at 1 mM. In bioassays, it has shown potent inhibitory activities against AmpC Beta-Lactamase (3162.3 nM) and ROR gamma transcriptional activity (707.9 nM). Despite these activities, it exhibits very low efficacy in displacing a fluorescent probe from human galectin-1, with a Kd greater than 10,000,000 nM, while showing moderate activity for human recombinant galectin-3 with a Kd of 4,400,000 nM. Thus, Methyl β-D-Galactopyranoside indicates potential in multiple biological pathways and target interactions..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Methyl β-D-Galactopyranoside is an endogenous metabolite with antifungal activity.
Synonyms	Methyl-β-D-galactopyranoside

Chemical Properties

Molecular Weight	194.18
Formula	C₇H₁₄O₆
Cas No.	1824-94-8
Smiles	CO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
Relative Density.	1.47 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (283.24 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.1499 mL	25.7493 mL	51.4986 mL	257.4930 mL
5 mM	1.0300 mL	5.1499 mL	10.2997 mL	51.4986 mL
10 mM	0.5150 mL	2.5749 mL	5.1499 mL	25.7493 mL
20 mM	0.2575 mL	1.2875 mL	2.5749 mL	12.8747 mL
50 mM	0.1030 mL	0.5150 mL	1.0300 mL	5.1499 mL
100 mM	0.0515 mL	0.2575 mL	0.5150 mL	2.5749 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc