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Anti-PSGL-1/CD162 Antibody (5Q473) (Synonyms: selectin P ligand, PSGL-1, PSGL1, CLA, CD162)

Catalog No. TMAY-02641 Copy Product Info
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Anti-PSGL-1/CD162 Antibody (5Q473) is a Mouse antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Antibody (5Q473) can be used in IHC-P.

Anti-PSGL-1/CD162 Antibody (5Q473)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02641
Synonyms selectin P ligand, PSGL-1, PSGL1, CLA, CD162

Anti-PSGL-1/CD162 Antibody (5Q473) is a Mouse antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Antibody (5Q473) can be used in IHC-P.

Anti-PSGL-1/CD162 Antibody
(5Q473)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PSGL-1/CD162 Antibody (5Q473) is a Mouse antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Antibody (5Q473) can be used in IHC-P.
Synonymsselectin P ligand, PSGL-1, PSGL1, CLA, CD162
Ig Type
Mouse IgG1
Clone
5Q473
Reactivity
Human
Specificity
Human PSGL-1/CD162
Verified Activity
1. Immunochemical staining of human SELPLG in human spleen with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.
2. Immunochemical staining of human SELPLG in human tonsil with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.
Application
Recommended Dose
IHC-P: 1:30-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis product is a recombinant monoclonal antibody expressed from HEK293 cells.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundP-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~12 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human PSGL-1/CD162/SELPLG Protein (TMPY-03531)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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