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Anti-EGFR Antibody-APC (5D853)
🥰Excellent
Catalog No. TMAY-00022A
Anti-EGFR Antibody-APC (5D853) is a APC-conjugated Mouse antibody targeting EGFR. Anti-EGFR Antibody-APC (5D853) can be used in FCM.
Anti-EGFR Antibody-APC (5D853)
Anti-EGFR Antibody-APC (5D853)
🥰Excellent
Catalog No. TMAY-00022A
Anti-EGFR Antibody-APC (5D853) is a APC-conjugated Mouse antibody targeting EGFR. Anti-EGFR Antibody-APC (5D853) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-EGFR Antibody-APC (5D853) is a APC-conjugated Mouse antibody targeting EGFR. Anti-EGFR Antibody-APC (5D853) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5D853 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of EGFR expression on human A431 cells. |
| Application | FCM |
| Recommended Dose | 1 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human EGFR / HER1 / ErbB1 (rh EGFR / HER1 / ErbB1; TMPY-00742; NP_005219; Met1-Ser645) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/Biotin/PE |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Human EGFR / HER1 / ErbB1 protein (TMPY-00742) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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