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Anti-Insulin Antibody (6L947) is a Rabbit antibody targeting Insulin. Anti-Insulin Antibody (6L947) can be used in ELISA,IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-Insulin Antibody (6L947) is a Rabbit antibody targeting Insulin. Anti-Insulin Antibody (6L947) can be used in ELISA,IHC-P. |
Alias | MODY10, IRDN, insulin, INS, ILPR, IDDM2, IDDM1, IDDM |
Ig Type | Monoclonal Rabbit IgG |
Clone | 6L947 |
Reactivity | Human |
Verified Activity | Immunochemical staining of human Insulin in human pancreas with rabbit monoclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections. |
Application | ELISA,IHC-P |
Recommended Dose | ELISA: 1:5000-1:10000; IHC-P: 1:200-1:1000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD28 (rh Insulin; TMPY-00395; P01308; Phe25-Lys53 & Gly90-Asn110). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with INS include Hyperproinsulinemia and Maturity-Onset Diabetes Of The Young, Type 10. A multitude of mutant alleles with phenotypic effects has been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes mellitus, maturity-onset diabetes of the young type 10, and hyperproinsulinemia.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
Conjucates | Unconjugated |
Immunogen | Recombinant Human Insulin Protein (TMPY-00395) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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