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HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled

Catalog No. TMPK-00452 Copy Product Info
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession number is P21860-1.

HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled

Catalog No. TMPK-00452
Copy Product Info

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession number is P21860-1.

HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$987-10 days7-10 days
10 μg$1687-10 days7-10 days
20 μg$2797-10 days7-10 days
50 μg$5527-10 days7-10 days
100 μg$9327-10 days7-10 days
200 μg$1,6807-10 days7-10 days
500 μg$3,7207-10 days7-10 days
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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)
For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

Product Information

Biological Activity
Immobilized FITC-Labeled Human Her3, His Tag at 5 μg/mL (100 μL/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 23.6 ng/mL determined by ELISA.
Description
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession number is P21860-1.
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberP21860-1
Synonyms
p85-sErbB3,p45-sErbB3,p180-ErbB3,MGC88033,MDA-BF-1,LCCS2,HER3c-erbB-3,HER3,ErbB-3,ErbB3
Construction
Ser20-Thr643
Protein Purity
> 95% as determined by Tris-Bis PAGE
Molecular Weight71.6 kDa (predicted). Due to glycosylation, the protein migrates to 72-75 kDa based on Tris-Bis PAGE result.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing HER-HM403F. Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).

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