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LILRA5/CD85f/ILT11 Protein, Human, Recombinant (hFc)

Catalog No. TMPY-04309
Synonyms: LILRB7, LIR9, leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5, ILT-11, CD85F, CD85, LIR-9, ILT11

LILRA5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LILR are a family of receptors possessing extracellular immunoglobulin domains. They are also known as CD85, ILTs, and LIR, and can exert immunomodulatory effects on a wide range of immune cells. ILT-11 contains 2 Ig-like C2-type (immunoglobulin-like) domains. It can be detected n tissues of the hematopoietic system, including bone marrow, spleen, lymph node, and peripheral leukocytes. Crosslink of ILT-11 on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses.

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LILRA5/CD85f/ILT11 Protein, Human, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 700.00
1 mg 5 days $ 4,570.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description LILRA5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LILR are a family of receptors possessing extracellular immunoglobulin domains. They are also known as CD85, ILTs, and LIR, and can exert immunomodulatory effects on a wide range of immune cells. ILT-11 contains 2 Ig-like C2-type (immunoglobulin-like) domains. It can be detected n tissues of the hematopoietic system, including bone marrow, spleen, lymph node, and peripheral leukocytes. Crosslink of ILT-11 on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses.
Species Human
Expression System HEK293
Tag hFc
Accession Number A6NI73-1
Synonyms LILRB7, LIR9, leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5, ILT-11, CD85F, CD85, LIR-9, ILT11
Construction A DNA sequence encoding the human LILRA5 (NP_067073.1) (Met1-Arg268) was expressed with the Fc region of human IgG1 at the C-terminus.
Protein Purity > 95 % as determined by SDS-PAGE.
Molecular Weight 52 kDa (predicted)
Endotoxin < 1.0 EU per μg protein as determined by the LAL method.
Formulation Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background LILRA5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LILR are a family of receptors possessing extracellular immunoglobulin domains. They are also known as CD85, ILTs, and LIR, and can exert immunomodulatory effects on a wide range of immune cells. ILT-11 contains 2 Ig-like C2-type (immunoglobulin-like) domains. It can be detected n tissues of the hematopoietic system, including bone marrow, spleen, lymph node, and peripheral leukocytes. Crosslink of ILT-11 on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses.

References and Literature

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Keywords

LILRA5/CD85f/ILT11 Protein, Human, Recombinant (hFc) ILT 11 CD 85 LILRB-7 LILRB7 LIR9 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 ILT-11 CD85F CD-85 CD85 LIR-9 LIR 9 LILRB 7 ILT11 recombinant recombinant-proteins proteins protein

 

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