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Anti-Phospho-CDC6 (S54) Antibody (7Q442)
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Catalog No. TMAC-03196
Anti-Phospho-CDC6 (S54) Antibody (7Q442) is a Rabbit antibody targeting Phospho-CDC6 (S54). Anti-Phospho-CDC6 (S54) Antibody (7Q442) can be used in WB,ICC/IF.
Anti-Phospho-CDC6 (S54) Antibody (7Q442)
Anti-Phospho-CDC6 (S54) Antibody (7Q442)
😃Good
Catalog No. TMAC-03196
Anti-Phospho-CDC6 (S54) Antibody (7Q442) is a Rabbit antibody targeting Phospho-CDC6 (S54). Anti-Phospho-CDC6 (S54) Antibody (7Q442) can be used in WB,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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| Description | Anti-Phospho-CDC6 (S54) Antibody (7Q442) is a Rabbit antibody targeting Phospho-CDC6 (S54). Anti-Phospho-CDC6 (S54) Antibody (7Q442) can be used in WB,ICC/IF. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division control (Cdc) genes are required at various points in the cell cycle. Cdc25A, Cdc25B and Cdc25C protein Tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory Tyrosine residues. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with HSP 90. Cdc34, Cdc27 and Cdc16 function as ubiquitin-conjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (x complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human Cdc6 around the phosphorylation site of Ser54 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 63 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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