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Anti-SMO Polyclonal Antibody (Synonyms: Smoothened homolog(Drosophila), Smoothened homolog precursor(SMO)(Gx pr...)

Catalog No. TMAB-01743 Copy Product Info
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Anti-SMO Polyclonal Antibody is a Rabbit antibody targeting SMO. Anti-SMO Polyclonal Antibody can be used in WB.

Anti-SMO Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-01743
Synonyms Smoothened homolog(Drosophila), Smoothened homolog precursor(SMO)(Gx protein), Smoothened homolog, Smoothened, SMOH, Gx

Anti-SMO Polyclonal Antibody is a Rabbit antibody targeting SMO. Anti-SMO Polyclonal Antibody can be used in WB.

Anti-SMO Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SMO Polyclonal Antibody is a Rabbit antibody targeting SMO. Anti-SMO Polyclonal Antibody can be used in WB.
SynonymsSmoothened homolog(Drosophila), Smoothened homolog precursor(SMO)(Gx protein), Smoothened homolog, Smoothened, SMOH, Gx
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Dog,Cow,Horse,Rabbit,Sheep)
Verified Activity
Sample:
Lane 1: Recombinant human Smoothened protein, His lysates
Primary: Anti-Smoothened (TMAB-01743) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 84 kDa
Observed band size: 28 kDa
verifiedActivity
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThe protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010] Function : G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SMO
Antigen Species
Human
Gene Name
SMO
Gene ID
Protein Name
Smoothened homolog
Uniprot ID
Biology Area
Neurogenesis,More GPCR,Transmembrane,GPCR,Surface Molecules
Function
G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
Chemical Properties
Molecular WeightTheoretical: 84 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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