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Ceftazidime Pentahydrate

Name: Ceftazidime Pentahydrate
Brand: TargetMol
SKU: T8261
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T8261Cas No. 78439-06-2

Ceftazidime Pentahydrate is a cephalosporin antibiotic with activity against gram-negative bacilli, including Pseudomonas aeruginosa, and is used in the study of infectious diseases.

Ceftazidime Pentahydrate

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Purity: 99.39%

Catalog No. T8261Cas No. 78439-06-2

Ceftazidime Pentahydrate is a cephalosporin antibiotic with activity against gram-negative bacilli, including Pseudomonas aeruginosa, and is used in the study of infectious diseases.

Pack Size	Price	USA Warehouse	Global Warehouse
200 mg	$29	In Stock	In Stock
500 mg	$42	In Stock	In Stock
1 g	$72	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.39%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Ceftazidime Pentahydrate is a cephalosporin antibiotic with activity against gram-negative bacilli, including Pseudomonas aeruginosa, and is used in the study of infectious diseases.
In vitro	In Pseudomonas aeruginosa strains (PAO1, PA1, PA2), Ceftazidime pentahydrate (approximately 0-8 µg/mL; 24 h) demonstrated antibacterial and anti-biofilm activities, with minimum inhibitory concentration (MIC) values of 2-4 µg/mL[2].
In vivo	In the murine thigh infection model, Ceftazidime Pentahydrate (2000 mg; administered via a 2-hour intravenous infusion every 8 hours for a total of 24 hours) was able to reduce the bacterial density against the isogenic NDM (New Delhi metallo-β-lactamase) strain[4].

Chemical Properties

Molecular Weight	636.65
Formula	C₂₂H₃₂N₆O₁₂S₂
Cas No.	78439-06-2
Smiles	CC1=CN2[C@H](SC1)[C@H](NC(=O)C(=N\OC(C)(C)C(O)=O)\c1csc(N)n1)C2=O
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (125.66 mM), Sonication is recommended.

H2O: 20 mg/mL (31.41 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.5707 mL	7.8536 mL	15.7072 mL	78.5361 mL
5 mM	0.3141 mL	1.5707 mL	3.1414 mL	15.7072 mL
10 mM	0.1571 mL	0.7854 mL	1.5707 mL	7.8536 mL
20 mM	0.0785 mL	0.3927 mL	0.7854 mL	3.9268 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0314 mL	0.1571 mL	0.3141 mL	1.5707 mL
100 mM	0.0157 mL	0.0785 mL	0.1571 mL	0.7854 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc