Shopping Cart

Your shopping cart is currently empty

Proceed to checkout Continue shopping

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine (Synonyms: (4-(4-methoxyphenyl)piperazin-1-yl)(2-(...)

Catalog No. T77598 Copy Product Info

Purity: 98.9%

🥰Excellent

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine ((4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone) is a raw material for biosynthesis and can be used to synthesize various compounds.

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine

Copy Product Info

🥰Excellent

Catalog No. T77598

Synonyms (4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine

Cas No. 906258-69-3

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
2 mg	$31	-	In Stock
5 mg	$52	-	In Stock
10 mg	$83	-	In Stock
25 mg	$180	-	In Stock
50 mg	$292	-	In Stock
100 mg	$405	-	In Stock
200 mg	$548	-	In Stock
1 mL x 10 mM (in DMSO)	$57	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

Custom-made molecule. TargetMol’s expert synthesis team delivers cost-effective solutions. Contact us for inquiries. Committed to serving you.

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:98.9%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine AI Summary

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine exhibits multifaceted bioactivities, functioning prominently as an inhibitor and modulator across various biochemical pathways. It acts as a modulator of miRNAs and an activator/inhibitor of miR-21 with a potency of 8260.4 nM and inhibits Tau fibril formation with a Thioflavin T binding potency of 15848.9 nM. Additionally, it effectively inhibits the Nrf2 pathway with a potency of 4610.9 nM, Histone Lysine Methyltransferase G9a at 3548.1 nM, and BAZ2B at 22387.2 nM. The compound also suppresses Polymerase Iota at 89125.1 nM, Lassa Virus binding/entry at 1584.9 nM, and ATXN expression at 39810.7 nM while activating BRCA1 expression with a potency of 1584.9 nM. It inhibits human tyrosyl-DNA phosphodiesterase 1 (TDP1) with potencies of 29092.9 nM (absence of CPT) and 23109.3 nM (presence of CPT) and shows inhibitory activity against PTHR with a potency of 125892.5 nM. Moreover, Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine is a potent inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 value of 2840.0 nM and achieving 89.8% inhibition at 33.33 µM relative to the control. Surface plasmon resonance (SPR) analysis reveals a binding affinity (Kd) to MAGL of 710.0 nM. Additionally, it shows inhibitory/activator effects on firefly luciferase with a potency of 19011.5 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine ((4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone) is a raw material for biosynthesis and can be used to synthesize various compounds.
Synonyms	(4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone

Chemical Properties

Molecular Weight	450.6
Formula	C₂₅H₃₀N₄O₂S
Cas No.	906258-69-3
Smiles	C(=O)(C=1C=C2C(N=C(S2)N3CCC(C)CC3)=CC1)N4CCN(CC4)C5=CC=C(OC)C=C5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 15 mg/mL (33.29 mM), Sonication and heating to 60℃ are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2193 mL	11.0963 mL	22.1926 mL	110.9632 mL
5 mM	0.4439 mL	2.2193 mL	4.4385 mL	22.1926 mL
10 mM	0.2219 mL	1.1096 mL	2.2193 mL	11.0963 mL
20 mM	0.1110 mL	0.5548 mL	1.1096 mL	5.5482 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: buy Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine | purchase Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine | Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine cost | order Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine | Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine chemical structure | Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine formula | Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine molecular weight