Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-CIB2 Antibody (3T556)

😃Good
Catalog No. TMAY-02393
Alias USH1J, KIP2, DFNB48, calcium and integrin binding family member 2

Anti-CIB2 Antibody (3T556) is a Rabbit antibody targeting CIB2. Anti-CIB2 Antibody (3T556) can be used in ELISA,ELISA(Det),IHC-P.

Anti-CIB2 Antibody (3T556)

Anti-CIB2 Antibody (3T556)

😃Good
Catalog No. TMAY-02393Alias USH1J, KIP2, DFNB48, calcium and integrin binding family member 2
Anti-CIB2 Antibody (3T556) is a Rabbit antibody targeting CIB2. Anti-CIB2 Antibody (3T556) can be used in ELISA,ELISA(Det),IHC-P.
Pack SizePriceAvailabilityQuantity
20 μL$94 7-10 days
100 μL$269 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-CIB2 Antibody (3T556) is a Rabbit antibody targeting CIB2. Anti-CIB2 Antibody (3T556) can be used in ELISA,ELISA(Det),IHC-P.
AliasUSH1J, KIP2, DFNB48, calcium and integrin binding family member 2
Ig Type
Monoclonal Rabbit IgG
Clone
3T556
Reactivity
Human
Verified Activity
1. Immunochemical staining of human CIB2 in human heart with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections).

2. Immunochemical staining of human CIB2 in human brain with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections).
Application
ELISA,ELISA(Det),IHC-P
Recommended Dose
ELISA: 1:5000-1:10000; IHC-P: 1:1000-1:4000; ELISA(Det): 1:1000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CIB2 (rh CIB2; TMPY-02289; O75838; Met 1-Ile 187).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCalcium and integrin-binding protein 2 (CIB2) belongs to a protein family with four known members, CIB1 through CIB4, which are characterized by multiple calcium-binding EF-hand domains. Sensorineural hearing loss is genetically heterogeneous. The mutations in CIB2, which encodes a calcium- and integrin-binding protein, are associated with nonsyndromic deafness (DFNB48) and Usher syndrome type 1J (USH1J). Furthermore, in zebrafish and Drosophila melanogaster, CIB2 is essential for the function and proper development of hair cells and retinal photoreceptor cells. We also show that CIB2 is a new member of the vertebrate Usher interactome. Variants in CIB2 can underlie either Usher syndrome type I (USH1J) or nonsyndromic hearing impairment (NSHI) (DFNB48). CIB2 is widely expressed in various human and animal tissues, mainly in skeletal muscle, nervous tissue, inner ear, and retina. The CIB2 protein is responsible for maintaining Ca(2+) homeostasis in cells and interacting with integrins-transmembrane receptors essential for cell adhesion, migration, and activation of signaling pathways. Calcium signaling pathway is crucial for signal transduction in the inner ear, and integrins regulate hair cell differentiation and maturation of the stereocilia.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human CIB2 protein (TMPY-02289)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-CIB2 Antibody (3T556) | purchase Anti-CIB2 Antibody (3T556) | Anti-CIB2 Antibody (3T556) cost | order Anti-CIB2 Antibody (3T556)