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Anti-HSPA5 Antibody (9M857)
😃Good
Catalog No. TMAC-01725
Alias Immunoglobulin heavy chain-binding protein, HSPA 5, HSP70 family protein 5, Heat shock protein family A member 5, Heat shock protein 70 family protein 5, GRP-78, GRP78, Endoplasmic reticulum chaperone BiP, EC 3.6.4.10, BiP, Binding-immunoglobulin protein, 78 kDa glucose-regulated protein
Anti-HSPA5 Antibody (9M857) is a Mouse antibody targeting HSPA5. Anti-HSPA5 Antibody (9M857) can be used in WB,ICC,IHC.
Anti-HSPA5 Antibody (9M857)
Anti-HSPA5 Antibody (9M857)
😃Good
Catalog No. TMAC-01725Alias Immunoglobulin heavy chain-binding protein, HSPA 5, HSP70 family protein 5, Heat shock protein family A member 5, Heat shock protein 70 family protein 5, GRP-78, GRP78, Endoplasmic reticulum chaperone BiP, EC 3.6.4.10, BiP, Binding-immunoglobulin protein, 78 kDa glucose-regulated protein
Anti-HSPA5 Antibody (9M857) is a Mouse antibody targeting HSPA5. Anti-HSPA5 Antibody (9M857) can be used in WB,ICC,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $428 | 7-10 days |
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Chemical Properties
| Description | Anti-HSPA5 Antibody (9M857) is a Mouse antibody targeting HSPA5. Anti-HSPA5 Antibody (9M857) can be used in WB,ICC,IHC. |
| Synonyms | Immunoglobulin heavy chain-binding protein, HSPA 5, HSP70 family protein 5, Heat shock protein family A member 5, Heat shock protein 70 family protein 5, GRP-78, GRP78, Endoplasmic reticulum chaperone BiP, EC 3.6.4.10, BiP, Binding-immunoglobulin protein, 78 kDa glucose-regulated protein |
| Clone | 9M857 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis on human spermatozoa lysates using anti- GRP78 mouse mAb. 2. ICC staining GRP78 in Hela cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:5000-10000; ICC: 1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Binding immunoglobulin protein (BiP) also known as 78 kDa glucose-regulated protein (GRP-78) or heat shock 70 kDa protein 5 (HSPA5) is a protein that in humans is encoded by the HSPA5 gene. BiP is a HSP70 molecular chaperone located in the lumen of the endoplasmic reticulum (ER) that binds newly synthesized proteins as they are translocated into the ER, and maintains them in a state competent for subsequent folding and oligomerization. BiP is also an essential component of the translocation machinery, as well as playing a role in retrograde transport across the ER membrane of aberrant proteins destined for degradation by the proteasome. Like many stress and heat shock proteins, BiP/GRP78 has potent immunological activity when released from the internal environment of the cell into the extracelluar space.specifically, it feeds inflammatory and pro-resolutory signals into immune networks, thus helping to resolve inflammation. |
| Conjucates | Unconjugated |
| Immunogen | Peptide |
| Uniprot ID |
| Molecular Weight | Theoretical: 78 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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