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Alkaline Phosphatase Protein, Human, Recombinant (aa 23-506, His)

Catalog No. TMPJ-00784
Synonyms: Alkaline phosphatase Regan isozyme, placental type, Placental alkaline phosphatase 1, ALPP and PLAP, Alkaline phosphatase

ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a role in a number of processes including cell signaling, long-term potentiation, and cell adhesion, however, the best known and most commonly studied role is implicated in Alzheimer's research.

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Alkaline Phosphatase Protein, Human, Recombinant (aa 23-506, His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 2,070.00
1 mg 5 days $ 2,970.00
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Biological Description
Technical Params
Product Properties
Description ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a role in a number of processes including cell signaling, long-term potentiation, and cell adhesion, however, the best known and most commonly studied role is implicated in Alzheimer's research.
Species Human
Expression System Human Cells
Tag C-6His
Accession Number P05187
Synonyms Alkaline phosphatase Regan isozyme, placental type, Placental alkaline phosphatase 1, ALPP and PLAP, Alkaline phosphatase
Amino Acid Ile23-Asp506
Construction Recombinant Human Alkaline Phosphatase, Placental Type is produced by our Mammalian expression system and the target gene encoding Ile23-Asp506 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
Molecular Weight 60-85 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.2mM CaCl<sub>2</sub>, 10% Glycerol, pH 7.5.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a role in a number of processes including cell signaling, long-term potentiation, and cell adhesion, however, the best known and most commonly studied role is implicated in Alzheimer's research.

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Keywords

Alkaline Phosphatase Protein, Human, Recombinant (aa 23-506, His) Alkaline phosphatase Regan isozyme placental type Placental alkaline phosphatase 1 ALPP and PLAP Alkaline phosphatase recombinant recombinant-proteins proteins protein

 

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