Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated

Catalog No. TMPJ-00283 Copy Product Info

Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. Appears to be a novel specific biomarker for a cervical neoplasia.

Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated

Catalog No. TMPJ-00283

Copy Product Info

Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated

Pack Size	Price	USA Stock	Global Stock
5 μg	$129	7-10 days	7-10 days
10 μg	$213	7-10 days	7-10 days
20 μg	$355	7-10 days	7-10 days
50 μg	$625	7-10 days	7-10 days
100 μg	$963	7-10 days	7-10 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	Immobilized Biotinylated Human CA9, His Avi Tag at 0.5 μg/ml (100 μl/well) on the streptavidin precoated plate (5 μg/ml). Dose response curve for Anti-CA9 Antibody, hFc Tag with the EC50 of 6.1 ng/ml determined by ELISA. (QC Test)
Description	Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. Appears to be a novel specific biomarker for a cervical neoplasia.
Species	Human
Expression System	HEK293 Cells
Tag	C-His-Avi
Accession Number	Q16790
Synonyms	RCC-associated protein G250,RCC,P54/58N,MN,G250,Carbonic Anhydrase IX,Carbonate dehydratase IX,CA-IX,CA9
Amino Acid	Gln38-Asp414
Construction	Gln38-Asp414
Protein Purity	> 95% as determined by Bis-Tris PAGE, > 95% as determined by HPLC
Molecular Weight	43.7 kDa (reducing condition), 52-65 kDa (due to glycosylation)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in 50mM Tris, 150mM NaCl (pH 7.5).
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. Appears to be a novel specific biomarker for a cervical neoplasia.