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Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated

(Synonyms: RCC-associated protein G250, RCC, P54/58N, MN, G250, Carbonic Anhydrase IX, Carbonate dehydratase IX, CA-IX, CA9) Copy Product Info

Synonyms: RCC-associated protein G250, RCC, P54/58N, MN, G250, Carbonic Anhydrase IX, Carbonate dehydratase IX, CA-IX, CA9

Catalog No. TMPJ-00283 Copy Product Info
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. Appears to be a novel specific biomarker for a cervical neoplasia.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$1297-10 days7-10 days
10 μg$2137-10 days7-10 days
20 μg$3557-10 days7-10 days
50 μg$6257-10 days7-10 days
100 μg$9637-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Biotinylated Human CA9, His Avi Tag at 0.5 μg/ml (100 μl/well) on the streptavidin precoated plate (5 μg/ml). Dose response curve for Anti-CA9 Antibody, hFc Tag with the EC50 of 6.1 ng/ml determined by ELISA. (QC Test)
Description
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. Appears to be a novel specific biomarker for a cervical neoplasia.
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberQ16790
Amino AcidGln38-Asp414
ConstructionGln38-Asp414
Protein Purity
> 95% as determined by Bis-Tris PAGE, > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in 50mM Tris, 150mM NaCl (pH 7.5).
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsRCC-associated protein G250, RCC, P54/58N, MN, G250, Carbonic Anhydrase IX, Carbonate dehydratase IX, CA-IX, CA9
Research Background
Chemical Properties
Molecular Weight43.7 kDa (reducing condition), 52-65 kDa (due to glycosylation)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated chemical structure | Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated molecular weight