Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively). It also decreases the activity of TNF-α converting enzyme (TACE) in a dose-dependent manner (IC50 = 0.54 μM). MMP-9 inhibitor I decreases TNF-α secretion stimulated by LPS in BV-2 microglial cells when used at concentrations of 50 and 100 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 363.00 |
Description | MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively). It also decreases the activity of TNF-α converting enzyme (TACE) in a dose-dependent manner (IC50 = 0.54 μM). MMP-9 inhibitor I decreases TNF-α secretion stimulated by LPS in BV-2 microglial cells when used at concentrations of 50 and 100 μM. |
Molecular Weight | 511.63 |
Formula | C27H33N3O5S |
CAS No. | 206549-55-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 20 mg/mL
DMSO: 25 mg/mL
Ethanol: 33 mg/mL
Ethanol:PBS (pH 7.2) (1:8): 0.11 mg/mL
You can also refer to dose conversion for different animals. More
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MMP-9 Inhibitor I 206549-55-5 MMP9 Inhibitor I MMP 9 Inhibitor I inhibitor inhibit