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JAM-A Protein, Human, Recombinant (His & Avi), Biotinylated
(Synonyms: UNQ264/PRO301, PAM-1, KAT, JCAM, JAM-A, JAMA, JAM-1, JAM1, JAM, CD321) Copy Product InfoSynonyms: UNQ264/PRO301, PAM-1, KAT, JCAM, JAM-A, JAMA, JAM-1, JAM1, JAM, CD321
Catalog No. TMPY-07004 Copy Product Info
JAM-A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is Q9Y624-1.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $167 | 7-10 days | 7-10 days | |
| 10 µg | $277 | 7-10 days | 7-10 days | |
| 20 µg | $462 | 7-10 days | 7-10 days | |
| 50 µg | $743 | 7-10 days | 7-10 days | |
| 100 µg | $1,220 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | JAM-A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is Q9Y624-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | Q9Y624-1 |
| Construction | A DNA sequence encoding the Human F11R (NP_058642.1) (Met1-Ala242) was expressed with a C-terminal polyhistidine tag followed by an AVI tag. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed. |
| Protein Purity | ≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Please refer to the lot-specific COA. |
| Synonyms | UNQ264/PRO301, PAM-1, KAT, JCAM, JAM-A, JAMA, JAM-1, JAM1, JAM, CD321 |
| Research Background | Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer. |
| Molecular Weight | 26.56 kDa (predicted); 34 kDa (reducing contition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: JAM-A Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | JAM-A Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight
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