Immobilized Human CD8 alpha, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-CD8 Antibody, hFc Tag with the EC50 of 10.3 ng/ml determined by ELISA

CD8 alpha Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is P01732-1.

Human

HEK293 Cells

p32,OKT8 T-cell antigen,MAL,Lyt-2,CD8a,CD8

Ser22-Asp182

> 95% as determined by Bis-Tris PAGE.

Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.