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Anti-COPS3 Antibody (7O525)
(Synonyms: Signalosome subunit 3, SGN3, JAB1-containing signalosome subunit 3, CSN3, COPS 3, COP9 signalosome complex subunit 3) Copy Product Info
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Synonyms: Signalosome subunit 3, SGN3, JAB1-containing signalosome subunit 3, CSN3, COPS 3, COP9 signalosome complex subunit 3
Catalog No. TMAH-00293 Copy Product Info
🥰Excellent
Anti-COPS3 Antibody (7O525) is an antibody targeting COPS3. Anti-COPS3 Antibody (7O525) can be used in ELISA,FCM,IF,IHC,WB.
Anti-COPS3 Antibody
(7O525)
(7O525)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-COPS3 Antibody (7O525) is an antibody targeting COPS3. Anti-COPS3 Antibody (7O525) can be used in ELISA,FCM,IF,IHC,WB. |
| Synonyms | Signalosome subunit 3, SGN3, JAB1-containing signalosome subunit 3, CSN3, COPS 3, COP9 signalosome complex subunit 3 |
| Ig Type | Rabbit IgG |
| Clone | 7O525 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:2000; IHC:1:50-1:200; IF:1:50-1:200; FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm. Nucleus. |
| Tissue Specificity | Widely expressed. Expressed at high level in heart and skeletal muscle. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human COPS3 |
| Antigen Species | Human |
| Gene Name | COPS3 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Neuroscience, Cell biology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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