Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mal-Pc, a phthalocyanine-based molecular photosensitizer featuring maleimides, interacts with GSH to diminish its levels and decrease aggregation, enhancing the ROS (Reactive Oxygen Species)-dependent efficacy of photodynamic therapy (PDT) in targeting cancer cells [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | Mal-Pc, a phthalocyanine-based molecular photosensitizer featuring maleimides, interacts with GSH to diminish its levels and decrease aggregation, enhancing the ROS (Reactive Oxygen Species)-dependent efficacy of photodynamic therapy (PDT) in targeting cancer cells [1]. |
In vitro | Mal-Pc, featuring two axial maleimide substituents, accelerates accumulation in cancer cells, enabling a reaction with GSH which leads to GSH depletion and reduced aggregation. This enhances the ROS-mediated anticancer efficacy of PDT [1]. Fluorescence imaging revealed that Mal-Pc is rapidly cleared from normal cells, attributed to the formation of a highly hydrophilic reaction product [1]. |
Molecular Weight | 876.86 |
Formula | C46H28N10O8Si |
CAS No. | 2670367-74-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Mal-Pc 2670367-74-3 Immunology/Inflammation Metabolism NF-Κb Reactive Oxygen Species inhibitor inhibit