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Naphazoline hydrochloride

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Catalog No. T0446Cas No. 550-99-2
Alias Rhinantin, Naphazoline HCl, Albalon

Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.

Naphazoline hydrochloride

Naphazoline hydrochloride

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Purity: 97.93%
Catalog No. T0446Alias Rhinantin, Naphazoline HCl, AlbalonCas No. 550-99-2
Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.
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Purity:97.93%
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Product Introduction

Bioactivity
Description
Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.
SynonymsRhinantin, Naphazoline HCl, Albalon
Chemical Properties
Molecular Weight246.74
FormulaC14H15ClN2
Cas No.550-99-2
SmilesCl.C(C1=NCCN1)c1cccc2ccccc12
Relative Density.1.15 g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 9 mg/mL (36.48 mM), Sonication is recommended.
Ethanol: 21 mg/mL (85.11 mM), Sonication is recommended.
H2O: 45 mg/mL (182.38 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (4.05 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/Ethanol/H2O
1mg5mg10mg50mg
1 mM4.0528 mL20.2642 mL40.5285 mL202.6425 mL
5 mM0.8106 mL4.0528 mL8.1057 mL40.5285 mL
10 mM0.4053 mL2.0264 mL4.0528 mL20.2642 mL
20 mM0.2026 mL1.0132 mL2.0264 mL10.1321 mL
Ethanol/H2O
1mg5mg10mg50mg
50 mM0.0811 mL0.4053 mL0.8106 mL4.0528 mL
H2O
1mg5mg10mg50mg
100 mM0.0405 mL0.2026 mL0.4053 mL2.0264 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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