Anti-Leptin Receptor Polyclonal Antibody 2

Name: Anti-Leptin Receptor Polyclonal Antibody 2
Brand: TargetMol
SKU: TMAB-01061
Rating: 4.5 (1 reviews)

(Synonyms: OB-R, OBR, leptin receptor, LEPRD, LEP-R, CD295) Copy Product Info

🥰Excellent

Synonyms: OB-R, OBR, leptin receptor, LEPRD, LEP-R, CD295

Catalog No. TMAB-01061 Copy Product Info

🥰Excellent

Anti-Leptin Receptor Polyclonal Antibody 2 is a Rabbit antibody targeting Leptin Receptor. Anti-Leptin Receptor Polyclonal Antibody 2 can be used in FCM,IF,IHC-Fr,IHC-P,WB.

Anti-Leptin Receptor Polyclonal Antibody 2

Pack Size	Price	USA Stock	Global Stock
50 μL	$221	7-10 days	7-10 days
100 μL	$372	7-10 days	7-10 days
200 μL	$529	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-Leptin Receptor Polyclonal Antibody 2 is a Rabbit antibody targeting Leptin Receptor. Anti-Leptin Receptor Polyclonal Antibody 2 can be used in FCM,IF,IHC-Fr,IHC-P,WB.
Synonyms	OB-R, OBR, leptin receptor, LEPRD, LEP-R, CD295
Ig Type	IgG
Reactivity	Human,Mouse,Rat (predicted:Horse,Sheep,Goat)

Application	FCM IF IHC-Fr IHC-P WB
Recommended Dose	WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 2ug/Test
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Cell membrane; Single-pass type I membrane protein. Isoform E: Secreted (Probable). Isoform A is expressed in fetal liver and in hematopoietic tissues and choroid plexus. In adults highest expression in heart, liver, small intestine, prostate and ovary. Low level in lung and kidney. Isoform B is highly expressed in hypothalamus.
Tissue Specificity	Isoform A is expressed in fetal liver and in hematopoietic tissues and choroid plexus. In adults highest expression in heart, liver, small intestine, prostate and ovary. Low level in lung and kidney. Isoform B is highly expressed in hypothalamus.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]

Antigen Details

Immunogen	KLH conjugated synthetic peptide: human Leptin receptor
Antigen Species	Human
Gene Name	LEPR
Gene ID	3953
Protein Name	Leptin receptor
Uniprot ID	P48357
Biology Area	Metabolism of lipids and lipoproteins,Metabolism,Fatty acids,Lipid metabolism,Fatty acid oxidation,Obesity,Hormones
Function	Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).