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Anti-AMH Antibody (5V998) (Synonyms: MIS, MIF, anti-Mullerian hormone)

Catalog No. TMAY-02833 Copy Product Info
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Anti-AMH Antibody (5V998) is a Mouse antibody targeting AMH. Anti-AMH Antibody (5V998) can be used in IHC-P.

Anti-AMH Antibody (5V998)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02833
Synonyms MIS, MIF, anti-Mullerian hormone

Anti-AMH Antibody (5V998) is a Mouse antibody targeting AMH. Anti-AMH Antibody (5V998) can be used in IHC-P.

Anti-AMH Antibody
(5V998)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-AMH Antibody (5V998) is a Mouse antibody targeting AMH. Anti-AMH Antibody (5V998) can be used in IHC-P.
SynonymsMIS, MIF, anti-Mullerian hormone
Ig Type
Mouse IgG1
Clone
5V998
Reactivity
Human
Specificity
Human MIS/AMH
Verified Activity
Immunochemical staining of human AMH in human testis with mouse monoclonal antibody at 1:30 dilution, formalin-fixed paraffin embedded sections.
Application
Recommended Dose
IHC-P: 1:20-1:50
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human AMH (rh AMH; TMPY-05176; NP_000470.2; Leu25-Arg560). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundAnti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and this process involves the SOX9 transcription factor. AMH is widely used for assessing ovarian reserve, and it is particularly convenient, because it is thought to have minimal variability throughout the menstrual cycle. Fetal anti-Mullerian hormone (AMH) is responsible for normal male sexual differentiation, and circulating AMH is used as a marker of testicular tissue in newborns with disorders of sex development. Anti-Mullerian hormone (AMH) produced in the developing testis induces the regression of the Mullerian duct, which develops into the oviducts, uterus and upper vagina. As well as other hormone receptors, and a decreased ovarian cortex cell proliferation. These results help understand the inhibitory effects of AMH on follicular development.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human AMH Protein (TMPY-05176)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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