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Anti-UGRP1 Polyclonal Antibody
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Catalog No. TMAB-01932
Alias Uteroglobin-Related Protein 1, UGRP1, Secretoglobin Family 3A Member 2, SCGB3A2, PnSP-1, PNSP1, Pneumo Secretory Protein 1
Anti-UGRP1 Polyclonal Antibody is a Rabbit antibody targeting UGRP1. Anti-UGRP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Anti-UGRP1 Polyclonal Antibody
Anti-UGRP1 Polyclonal Antibody
😃Good
Catalog No. TMAB-01932Alias Uteroglobin-Related Protein 1, UGRP1, Secretoglobin Family 3A Member 2, SCGB3A2, PnSP-1, PNSP1, Pneumo Secretory Protein 1
Anti-UGRP1 Polyclonal Antibody is a Rabbit antibody targeting UGRP1. Anti-UGRP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-UGRP1 Polyclonal Antibody is a Rabbit antibody targeting UGRP1. Anti-UGRP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
| Synonyms | Uteroglobin-Related Protein 1, UGRP1, Secretoglobin Family 3A Member 2, SCGB3A2, PnSP-1, PNSP1, Pneumo Secretory Protein 1 |
| Ig Type | IgG |
| Reactivity | (predicted:Human,Mouse,Rat,Pig,Horse) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Uteroglobin-related protein 1 is a 93-amino acid secretory protein that is mainly expressed in lung Clara-like epithelial cells, with low levels of expression in the thyroid. The homodimeric UGRP1 may play an anti-inflammatory role in lung inflammation, though the mechanism is still unknown. A macrophage scavenger receptor with collagenous structure (MARCO) acts as a receptor for UGRP1 and may be involved in pathogen clearance in the lung. UGRP1 has a binding site for bacterial lipopolysaccharide (LPS). It is downregulated in antigen-induced inflamed airways, such as allergic asthma, but is upregulated in cystic fibrosis, and interleukin-9 and interleukin-5 modulate UGRP1 expression. UGRP1 may be a therapeutic candidate for treating various sources of lung inflammation |
| Immunogen | KLH conjugated synthetic peptide: human SCGB3A2 |
| Antigen Species | Human |
| Gene Name | SCGB3A2 |
| Gene ID | |
| Protein Name | Secretoglobin family 3A member 2 |
| Uniprot ID | |
| Biology Area | Other factors |
| Function | In addition to regulating thyroid-specific expression of genes, thyroid transcription factor controls the transcription of genes specifically expressed in lung, such as surfactant proteins and uteroglobin. Mice lacking Ttf1 die immediately after birth from respiratory failure caused by profoundly hypoplastic lungs. The UGRP1 gene encodes a uteroglobin-related protein and is a downstream target of TITF1. |
| Molecular Weight | Theoretical: 8 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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