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Prostaglandin D2 Ethanolamide

Name: Prostaglandin D2 Ethanolamide
Brand: TargetMol
SKU: T38389
Rating: 4.5 (1 reviews)

(Synonyms: PGD2 ethanolamide) Copy Product Info

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Synonyms: PGD2 ethanolamide

Catalog No. T38389 Copy Product Info

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Prostaglandin D2 Ethanolamide is a metabolite generated from arachidonoyl ethanolamide via the COX-2 pathway, which induces apoptosis in colorectal cancer cells.

Cas No. 398138-28-8

Pack Size	Price	USA Stock	Global Stock	Quantity
1 mg	$276	35 days	35 days
5 mg	$1,190	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Liquid

Color:Transparent

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COA

Product Introduction

Bioactivity

Description	Prostaglandin D2 Ethanolamide is a metabolite generated from arachidonoyl ethanolamide via the COX-2 pathway, which induces apoptosis in colorectal cancer cells.
In vitro	Methods: Colorectal cancer cell lines were treated with different concentrations of Prostaglandin D2 Ethanolamide (1–10 μM) for 72 h to detect its effects on cell growth and survival. Results: Prostaglandin D2 Ethanolamide (1–10 μM, treatment for 72 h) could inhibit cell proliferation and induce cell death in colorectal cancer (CRC) cell lines [1].
Synonyms	PGD2 ethanolamide

Chemical Properties

Molecular Weight	395.53
Formula	C₂₂H₃₇NO₅
Cas No.	398138-28-8
Smiles	C(=C/[C@H](CCCCC)O)\[C@@H]1[C@@H](C/C=C\CCCC(NCCO)=O)[C@@H](O)CC1=O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 4.15 mg/mL (10.49 mM), Sonication is recommended.

DMF: 4.15 mg/mL (10.49 mM), Sonication is recommended.

Ethanol: 6.25 mg/mL (15.8 mM), Sonication is recommended.

PBS (pH 7.2): 1.25 mg/mL (3.16 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMSO/DMF/Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.5283 mL	12.6413 mL	25.2825 mL	126.4127 mL

DMSO/DMF/Ethanol

	1mg	5mg	10mg	50mg
5 mM	0.5057 mL	2.5283 mL	5.0565 mL	25.2825 mL
10 mM	0.2528 mL	1.2641 mL	2.5283 mL	12.6413 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Keywords

Prostaglandin D-2 EthanolamideProstaglandin D2 Ethanolamide

Related Tags: Prostaglandin D2 Ethanolamide chemical structure | Prostaglandin D2 Ethanolamide in vitro | Prostaglandin D2 Ethanolamide formula | Prostaglandin D2 Ethanolamide molecular weight