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Anti-ALDH7A1 Antibody (6G475)
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Catalog No. TMAY-01932
Alias PDE, EPD, ATQ1, aldehyde dehydrogenase 7 family, member A1
Anti-ALDH7A1 Antibody (6G475) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (6G475) can be used in IHC-P.
Anti-ALDH7A1 Antibody (6G475)
Anti-ALDH7A1 Antibody (6G475)
😃Good
Catalog No. TMAY-01932Alias PDE, EPD, ATQ1, aldehyde dehydrogenase 7 family, member A1
Anti-ALDH7A1 Antibody (6G475) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (6G475) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: IHC-P Reactivity: Human |
| Alias | PDE, EPD, ATQ1, aldehyde dehydrogenase 7 family, member A1 |
| Ig Type | Mouse IgG1 |
| Clone | 6G475 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human ALDH7A1 in human hepatoma with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human ALDH7A1 in human cirrhosis with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). The image showing positive staining of hepatocyte. |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ALDH7A1 (rh ALDH7A1; TMPY-01588; P49419-2; Ser2-Gln511). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Mammalian ALDH7A1 is homologous to plant ALDH7B1 which protects against various forms of stress such as increased salinity, dehydration and treatment with oxidants or pesticides. In mammals, ALDH7A1 is known to play a primary role during lysine catabolism through the NAD+-dependent oxidative conversion of aminoadipate semialdehyde (AASA) to its corresponding carboxylic acid, α-aminoadipic acid. Deleterious mutations in human ALDH7A1 are responsible for pyridoxine-dependent and folinic acid-responsive seizures. ALDH7A1 is a novel aldehyde dehydrogenase expressed in multiple subcellular compartments that protects against hyperosmotic stress by generating osmolytes and metabolizing toxic aldehydes. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ALDH7A1 protein (TMPY-01588) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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