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ABBV-969 Payload

Name: ABBV-969 Payload
Brand: TargetMol
SKU: T74751
Rating: 4.5 (1 reviews)

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Catalog No. T74751Cas No. 2857037-70-6

Alias Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT

ABBV-969 Payload (Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT) is a drug-linker conjugate for the synthesis of ADCs containing a Topo I (Topoisomerase 1) inhibitor molecule and a linker molecule, which can be coupled with anti-c-Met antibodies to form ABBV- 969.

ABBV-969 Payload

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Catalog No. T74751Alias Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPTCas No. 2857037-70-6

Pack Size	Price	Availability
1 mg	$689	10-14 weeks
5 mg	$1,700	10-14 weeks
10 mg	$2,780	10-14 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	ABBV-969 Payload (Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT) is a drug-linker conjugate for the synthesis of ADCs containing a Topo I (Topoisomerase 1) inhibitor molecule and a linker molecule, which can be coupled with anti-c-Met antibodies to form ABBV- 969.
Alias	Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT

Chemical Properties

Molecular Weight	764.62
Formula	C₃₆H₃₈BrN₅O₉
Cas No.	2857037-70-6

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 80 mg/mL (104.63 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3078 mL	6.5392 mL	13.0784 mL	65.3920 mL
5 mM	0.2616 mL	1.3078 mL	2.6157 mL	13.0784 mL
10 mM	0.1308 mL	0.6539 mL	1.3078 mL	6.5392 mL
20 mM	0.0654 mL	0.3270 mL	0.6539 mL	3.2696 mL
50 mM	0.0262 mL	0.1308 mL	0.2616 mL	1.3078 mL
100 mM	0.0131 mL	0.0654 mL	0.1308 mL	0.6539 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc