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IL-5R alpha/CD125 Protein, Mouse, Recombinant (His)
(Synonyms: interleukin 5 receptor, α, interleukin 5 receptor, alpha, Il5r, CDw125, CD125) Copy Product InfoSynonyms: interleukin 5 receptor, α, interleukin 5 receptor, alpha, Il5r, CDw125, CD125
Catalog No. TMPY-03522 Copy Product Info
IL-5R alpha/CD125 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 36.87 kDa and the accession number is P21183.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $93 | 7-10 days | 7-10 days | |
| 10 µg | $152 | 7-10 days | 7-10 days | |
| 20 µg | $248 | 7-10 days | 7-10 days | |
| 50 µg | $498 | 7-10 days | 7-10 days | |
| 100 µg | $858 | 7-10 days | 7-10 days | |
| 200 µg | $1,530 | 7-10 days | 7-10 days | |
| 500 µg | $3,790 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | IL-5R alpha/CD125 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 36.87 kDa and the accession number is P21183. |
| Species | Mouse |
| Expression System | Baculovirus Insect Cells |
| Tag | C-His |
| Accession Number | P21183 |
| Construction | A DNA sequence encoding the mouse IL5Ra (P21183) (Met1-Val328) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Asp 18 |
| Protein Purity | > 95 % as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 500 mM NaCl, 10% gly, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Synonyms | interleukin 5 receptor, α, interleukin 5 receptor, alpha, Il5r, CDw125, CD125 |
| Research Background | Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA (CD125) is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand-specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony-stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported. IL5RA (CD125) is a T-cell-derived cytokine that is particularly important in the development of asthma for the terminal differentiation, activation, and survival of committed eosinophil precursors. |
| Molecular Weight | 36.87 kDa (predicted); 45 kDa (reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: IL-5R alpha/CD125 Protein, Mouse, Recombinant (His) chemical structure | IL-5R alpha/CD125 Protein, Mouse, Recombinant (His) molecular weight
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