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Teriflunomide impurity 3

Name: Teriflunomide impurity 3
Brand: TargetMol
SKU: T9042
Price: 318 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9042Cas No. 1011244-72-6

Alias 4-Amino-N-(4-trifluoromethylphenyl)benzamide

Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor with an IC50 of 30 μM and exhibits less activity against COX-2 (IC50 > 100 μM).

Teriflunomide impurity 3

🥰Excellent

Purity: 99.62%

Catalog No. T9042Alias 4-Amino-N-(4-trifluoromethylphenyl)benzamideCas No. 1011244-72-6

Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor with an IC50 of 30 μM and exhibits less activity against COX-2 (IC50 > 100 μM).

Pack Size	Price	Availability
10 mg	$43	In Stock
25 mg	$83	In Stock
50 mg	$136	In Stock
100 mg	$223	In Stock
200 mg	$318	In Stock
500 mg	Preferential	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock

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Batch Information

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Purity:99.62%

Resource Download

COA LCMS HPLC HNMR

Product Introduction

Bioactivity

Description	Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor with an IC50 of 30 μM and exhibits less activity against COX-2 (IC50 > 100 μM).
Targets&IC50	COX-1:30 μM, COX-2:>100 µM
Synonyms	4-Amino-N-(4-trifluoromethylphenyl)benzamide

Chemical Properties

Molecular Weight	280.25
Formula	C₁₄H₁₁F₃N₂O
Cas No.	1011244-72-6
Smiles	Nc1ccc(cc1)C(=O)Nc1ccc(cc1)C(F)(F)F
Relative Density.	1.373 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (892.06 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5682 mL	17.8412 mL	35.6824 mL	178.4121 mL
5 mM	0.7136 mL	3.5682 mL	7.1365 mL	35.6824 mL
10 mM	0.3568 mL	1.7841 mL	3.5682 mL	17.8412 mL
20 mM	0.1784 mL	0.8921 mL	1.7841 mL	8.9206 mL
50 mM	0.0714 mL	0.3568 mL	0.7136 mL	3.5682 mL
100 mM	0.0357 mL	0.1784 mL	0.3568 mL	1.7841 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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