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Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor with an IC50 of 30 μM and exhibits less activity against COX-2 (IC50 > 100 μM).

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $43 | In Stock | In Stock | |
| 25 mg | $83 | In Stock | In Stock | |
| 50 mg | $136 | In Stock | In Stock | |
| 100 mg | $223 | In Stock | In Stock | |
| 200 mg | $318 | In Stock | In Stock | |
| 500 mg | Preferential | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $30 | In Stock | In Stock |
| Description | Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor with an IC50 of 30 μM and exhibits less activity against COX-2 (IC50 > 100 μM). |
| Targets&IC50 | COX-1:30 μM, COX-2:>100 µM |
| Synonyms | 4-Amino-N-(4-trifluoromethylphenyl)benzamide |
| Molecular Weight | 280.25 |
| Formula | C14H11F3N2O |
| Cas No. | 1011244-72-6 |
| Smiles | Nc1ccc(cc1)C(=O)Nc1ccc(cc1)C(F)(F)F |
| Relative Density. | 1.373 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 250 mg/mL (892.06 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+90% Corn Oil: 3.3 mg/mL (11.78 mM), Sonication is recommeded. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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