Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MEK/PI3K-IN-1 (compound 6r) is a potent inhibitor targeting both MEK and PI3K, exhibiting IC50 values of 124 nM for MEK1, 130 nM for PI3Kα, and 236 nM for PI3Kδ. It effectively reduces levels of pAKT and pERK1/2, demonstrating anti-proliferative effects on various tumor cell lines [1].
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Description | MEK/PI3K-IN-1 (compound 6r) is a potent inhibitor targeting both MEK and PI3K, exhibiting IC50 values of 124 nM for MEK1, 130 nM for PI3Kα, and 236 nM for PI3Kδ. It effectively reduces levels of pAKT and pERK1/2, demonstrating anti-proliferative effects on various tumor cell lines [1]. |
Molecular Weight | 913.63 |
Formula | C36H37F5IN9O6 |
CAS No. | 2281803-28-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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MEK/PI3K-IN-1 2281803-28-7 inhibitor inhibit