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Synonyms: APM1, ACDC


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $85 | 7-10 days | 7-10 days | |
| 10 µg | $138 | 7-10 days | 7-10 days | |
| 20 µg | $197 | 7-10 days | 7-10 days | |
| 50 µg | $339 | 7-10 days | 7-10 days | |
| 100 µg | $573 | 7-10 days | 7-10 days | |
| 200 µg | $977 | 7-10 days | 7-10 days | |
| 500 µg | $1,980 | 7-10 days | 7-10 days | |
| 1 mg | $3,390 | 7-10 days | 7-10 days |
| Bioactivity | ED 50 < 2.0 µg/ml, measured by a cell proliferation assay using M1 cells, corresponding to a specific activity of > 500.0 units/mg. |
| Description | Adiponectin Protein, Mouse, Recombinant (V113M) is expressed in E. coli. The accession number is Q60994. |
| Species | Mouse |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | Q60994 |
| Construction | Lys104-Asn247 (Val113Met) |
| Protein Purity | > 95% as determined by SDS-PAGE; > 95% as determined by HPLC |
| Endotoxin | < 0.2 EU/μg of protein as determined by the LAL method. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | APM1, ACDC |
| Research Background | gAcrp30 is the globular head domain of Adipocyte complement-related protein of 30 kDa (Acrp30), a cytokine expressed in adipocytes. The name of Acrp30 is bases on its closest homolog, complement factor c1q, and the globular domain of Acrp30 has an unexpected homology with the Tumor Necrosis Factor (TNF) family of cytokines. Acrp30 is recognized by two receptors: adipoR1 expressed in skeletal muscle, and adipoR2 expressed in liver. The expression level of Acrp30 in adipocytes is negatively correlated with body weight and is lower in obese mouse than normal mouse. The globular domain of Acrp30 induces free fatty acid oxidation in muscle and weight reduction in mouse, suggesting its potential use as a pharmacological agent in obesity. |
| Molecular Weight | ~16.5 kDa (Non-reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
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