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Anti-VCAM-1 Polyclonal Antibody
(Synonyms: VCAM-1, vascular cell adhesion molecule 1, INCAM-100, CD106) Copy Product Info
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Synonyms: VCAM-1, vascular cell adhesion molecule 1, INCAM-100, CD106
Catalog No. TMAB-01941 Copy Product Info
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Anti-VCAM-1 Polyclonal Antibody is a Rabbit antibody targeting VCAM-1. Anti-VCAM-1 Polyclonal Antibody can be used in WB.
Anti-VCAM-1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-VCAM-1 Polyclonal Antibody is a Rabbit antibody targeting VCAM-1. Anti-VCAM-1 Polyclonal Antibody can be used in WB. |
| Synonyms | VCAM-1, vascular cell adhesion molecule 1, INCAM-100, CD106 |
| Ig Type | IgG |
| Reactivity | Mouse |
| Application | |
| Recommended Dose | WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Lipid-anchor, GPI-anchor. |
| Tissue Specificity | Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. Expressed in the bone marrow. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | VCAM1 is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the integrins alpha4 beta1 (beta 1 integrin VLA4) and alpha4 beta7 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. VCAM1 is also expressed by several non endothelial cell types including some macrophages, follicular dendritic cells and bone marrow, stromal cells. |
| Immunogen | Recombinant Protein: Mouse VCAM 1 protein |
| Antigen Species | Mouse |
| Gene Name | VCAM1 |
| Protein Name | Vascular cell adhesion protein 1 |
| Biology Area | Cell adhesion,Endothelial Cell Markers,Cell adhesion molecules,Adhesion molecules ELISA kits,Atherosclerotic proteins ELISA kits,SARS Coronavirus,Neural Signal Transduction,Endothelial,Vascular,Surface Molecules |
| Function | Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |
| Molecular Weight | Theoretical: 81 kDa. Actual: 100 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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