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Anti-VCAM-1 Polyclonal Antibody is a Rabbit antibody targeting VCAM-1. Anti-VCAM-1 Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $221 | 7-10 days | |
100 μL | $373 | 7-10 days |
Description | Antibody Type: Rabbit Polyclonal Application: WB Reactivity: Mouse |
Ig Type | IgG |
Reactivity | Mouse |
Verified Activity | Sample: Lane 1: Mouse Kidney tissue lysates Lane 2: Mouse Spleen tissue lysates Lane 3: Mouse Cerebrum tissue lysates Primary: Anti-VCAM1 (TMAB-01941) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 81 kDa Observed band size: 100 kDa |
Application | WB |
Recommended Dose | WB: 1:200-1000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Lipid-anchor, GPI-anchor. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | VCAM1 is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the integrins alpha4 beta1 (beta 1 integrin VLA4) and alpha4 beta7 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. VCAM1 is also expressed by several non endothelial cell types including some macrophages, follicular dendritic cells and bone marrow, stromal cells. |
Immunogen | Recombinant Protein: Mouse VCAM 1 protein |
Antigen Species | Mouse |
Biology Area | Cell adhesion,Endothelial Cell Markers,Cell adhesion molecules,Adhesion molecules ELISA kits,Atherosclerotic proteins ELISA kits,SARS Coronavirus,Neural Signal Transduction,Endothelial,Vascular,Surface Molecules |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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