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Anti-Phospho-PTPN11 (Tyr542) Antibody (1U332)
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Catalog No. TMAC-03265
Alias PTPN11 (p-Y542), PTPN11 (p-Tyr542), p-PTPN11 (Y542), p-PTPN11 (Tyr542)
Anti-Phospho-PTPN11 (Y542) Antibody (1U332) is a Rabbit antibody targeting Phospho-PTPN11 (Y542). Anti-Phospho-PTPN11 (Y542) Antibody (1U332) can be used in WB,ICC,IP.
Anti-Phospho-PTPN11 (Tyr542) Antibody (1U332)
Anti-Phospho-PTPN11 (Tyr542) Antibody (1U332)
😃Good
Catalog No. TMAC-03265Alias PTPN11 (p-Y542), PTPN11 (p-Tyr542), p-PTPN11 (Y542), p-PTPN11 (Tyr542)
Anti-Phospho-PTPN11 (Y542) Antibody (1U332) is a Rabbit antibody targeting Phospho-PTPN11 (Y542). Anti-Phospho-PTPN11 (Y542) Antibody (1U332) can be used in WB,ICC,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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Product Introduction
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Chemical Properties
| Description | Anti-Phospho-PTPN11 (Tyr542) Antibody (1U332) is a Rabbit antibody targeting Phospho-PTPN11 (Tyr542). Anti-Phospho-PTPN11 (Tyr542) Antibody (1U332) can be used in WB,ICC,IP. |
| Synonyms | PTPN11 (p-Y542), PTPN11 (p-Tyr542), p-PTPN11 (Y542), p-PTPN11 (Tyr542) |
| Ig Type | IgG |
| Clone | 1U332 |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of phospho-SHP2 (Y542) on NIH/3T3 lysates using anti-phospho-SHP2 (Y542) antibody at 1/1,000 dilution. 2. ICC staining phospho-SHP2 (Y542) in B-6F1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000; ICC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non-transmembrane PTP, designated SH-PTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. SH2 domains generally mediate the association of regulatory molecules with specific phosphotyrosine-containing sites on autophosphorylated receptors, thereby controlling the initial interaction of receptors with these substrates. A second and much more widely expressed PTP with SH2 domains, SH-PTP2 (also designated PTP1D and Syp), has been identified. Strong sequence similarity between SH-PTP2 and the Drosophila gene corkscrew (CSW) and their similar patterns of expression suggest that SH-PTP2 is the human corkscrew homolog. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human SHP2 around the phosphorylation site of Tyr542 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 68 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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