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Epitalon
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Catalog No. TP1456Cas No. 307297-39-8
Alias Epithalon, Epithalamin
Epithalon (Epitalon, Epithalone) is the synthetic form of the pineal gland-derived polypeptide epithalamin.
Epitalon
🥰Excellent
Purity: 99.97%
Catalog No. TP1456Alias Epithalon, EpithalaminCas No. 307297-39-8
Epithalon (Epitalon, Epithalone) is the synthetic form of the pineal gland-derived polypeptide epithalamin.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $85 | - | In Stock | |
| 5 mg | $193 | - | In Stock | |
| 10 mg | $293 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.97%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Epithalon (Epitalon, Epithalone) is the synthetic form of the pineal gland-derived polypeptide epithalamin. |
| In vitro | Epitalon (0.1, 0.2, 0.5 to 1 μg/ml, 4 days) dose-dependently increased telomere length in 21NT and BT474 breast cancer cells [1]. |
| In vivo | Epitalon (30-40 microg/kg, intravenous injection, administered for 5 consecutive days per month) did not affect food consumption, body weight, or average lifespan in mice; however, it delayed age-related decline in estrous function and reduced the rate of chromosomal aberrations in bone marrow cells (a decrease of 17.1%, P<0.05) [2]. |
| Synonyms | Epithalon, Epithalamin |
| Molecular Weight | 390.35 |
| Formula | C14H22N4O9 |
| Cas No. | 307297-39-8 |
| Smiles | [C@@H](NC([C@@H](NC([C@H](C)N)=O)CCC(O)=O)=O)(C(NCC(O)=O)=O)CC(O)=O |
| Relative Density. | 1.466 g/cm3 (Predicted) |
| Color | White |
| Appearance | Solid |
| Sequence | H-Ala-Glu-Asp-Gly-OH |
| Sequence Short | AEDG |
Storage & Solubility Information
| Storage | keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: ≥ 40 mg/mL, Sonication is recommeded. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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