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Anti-Phospho-BTK (Tyr223) Polyclonal Antibody

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Catalog No. TMAC-00484

Anti-Phospho-BTK (Tyr223) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BTK (Tyr223). Anti-Phospho-BTK (Tyr223) Polyclonal Antibody can be used in WB.

Anti-Phospho-BTK (Tyr223) Polyclonal Antibody

Anti-Phospho-BTK (Tyr223) Polyclonal Antibody

😃Good
Catalog No. TMAC-00484
Anti-Phospho-BTK (Tyr223) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BTK (Tyr223). Anti-Phospho-BTK (Tyr223) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2187-10 days
100 μL$3167-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-BTK (Tyr223) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BTK (Tyr223). Anti-Phospho-BTK (Tyr223) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundNon-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 223 (A-L-Y(p)-D-Y) derived from Human BTK
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 80 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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