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Synonyms: PTGDS2, Prostaglandin-H2 D-Isomerase, PGDS, H-PGDS, HPGDS, Hematopoietic Prostaglandin D Synthase, GSTS, GST Class-σ, GST Class-Sigma, Glutathione-Requiring Prostaglandin D Synthase, Glutathione-Dependent PGD Synthase, Glutathione S-Transferase

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $183 | 6-8 weeks | 6-8 weeks | |
| 20 µg | $292 | 6-8 weeks | 6-8 weeks | |
| 50 µg | $545 | 6-8 weeks | 6-8 weeks | |
| 100 µg | $813 | 6-8 weeks | 6-8 weeks | |
| 200 µg | $1,190 | 6-8 weeks | 6-8 weeks | |
| 500 µg | $2,070 | 6-8 weeks | 6-8 weeks | |
| 1 mg | $2,970 | 6-8 weeks | 6-8 weeks |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide. |
| Species | Human |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | O60760 |
| Amino Acid | Met1-Leu199 |
| Construction | Met1-Leu199 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 200 mM NaCl, pH 7.0. |
| Synonyms | PTGDS2, Prostaglandin-H2 D-Isomerase, PGDS, H-PGDS, HPGDS, Hematopoietic Prostaglandin D Synthase, GSTS, GST Class-σ, GST Class-Sigma, Glutathione-Requiring Prostaglandin D Synthase, Glutathione-Dependent PGD Synthase, Glutathione S-Transferase |
| Research Background | Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide. |
| Molecular Weight | 26 KDa (reducing condition) |
| Shipping | Proteins are shipped with blue ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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