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HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi)

Catalog No. TMPK-01546
Synonyms: MHC, CT6.1, CTAG1, MY-ESO-1, ESO1CTAG, CTAG1B, NY-ESO-1, LAGE-2, LAGE2A

NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi)
Pack Size Availability Price/USD Quantity
100 μg Inquiry $ 489.00
1 mg Inquiry $ 3,265.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
Species Human
Expression System HEK293
Tag C-His-Avi
Accession Number A0A140T913(HLA-A*02:01)&P61769(B2M)&SLLMWITQC
Synonyms MHC, CT6.1, CTAG1, MY-ESO-1, ESO1CTAG, CTAG1B, NY-ESO-1, LAGE-2, LAGE2A
Construction Recombinant Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus,tetramer is assembled by biotinylated monomer and streptavidin. It contains Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M) and SLLMWITQC peptide.[Accession |A0A140T913(HLA-A*02:01)&P61769(B2M)&SLLMWITQC]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Supplied as 0.22μm filtered solution in 20mM PB, 500mM NaCl (pH 7.4).
Stability & Storage

Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.

References and Literature

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Keywords

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi) MHC CT6.1 CTAG1 MY-ESO-1 ESO1CTAG CTAG1B NY-ESO-1 LAGE-2 LAGE2A recombinant recombinant-proteins proteins protein

 

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