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Anti-TNFR2/CD120b/TNFR1B Antibody (1J191)

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Catalog No. TMAB-01874

Anti-TNFR2/CD120b/TNFR1B Antibody (1J191) is a Rabbit antibody targeting TNFR2/CD120b/TNFR1B. Anti-TNFR2/CD120b/TNFR1B Antibody (1J191) can be used in IHC-P,IHC-Fr,IF.

Anti-TNFR2/CD120b/TNFR1B Antibody (1J191)

Anti-TNFR2/CD120b/TNFR1B Antibody (1J191)

😃Good
Catalog No. TMAB-01874
Anti-TNFR2/CD120b/TNFR1B Antibody (1J191) is a Rabbit antibody targeting TNFR2/CD120b/TNFR1B. Anti-TNFR2/CD120b/TNFR1B Antibody (1J191) can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceAvailabilityQuantity
50 μL$273 7-10 days
100 μL$487 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: IHC-P,IHC-Fr,IF

Reactivity: Human (predicted:Mouse,Rat)
Ig Type
IgG
Clone
1J191
Reactivity
Human (predicted:Mouse,Rat)
Verified Activity
1. Sample:
Lane 1: Human THP-1 cell Lysates
Lane 2: Human K562 cell Lysates
Lane 3: Human U937 cell Lysates
Lane 4: Human U87MG cell Lysates
Lane 5: Human HUVEC cell Lysates
Primary: Anti-TNFR2 (TMAB-01874) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kDa
Observed band size: 70 kDa
2. Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TNFR2 Monoclonal Antibody, Unconjugated (TMAB-01874) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Human Chronic tonsillitis; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TNFR2 Monoclonal Antibody, Unconjugated (TMAB-01874) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Human Kidney Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TNFR2 Monoclonal Antibody, Unconjugated (TMAB-01874) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
Application
IHC-P,IHC-Fr,IF
Recommended Dose
IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted and Cell membrane.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThe protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
A synthesized peptide: human TNFRSF1B
Antigen Species
Human
Gene ID
7133
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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