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TargetMol | Compound Library

Approved Drug Library

Catalog No. L1000

Traditional de novo drug discovery and development involves an HTS campaign for de novo candidate hits and requires highly specialized screening facilities and compound libraries containing several million compounds. It is a time consuming and expensive process. As the regulation for drug safety and efficacy is increasingly getting complex, the cost of developing new drugs is keeping skyrocket. Drug repositioning, also known as old drugs for new uses, is an effective strategy to find new indications for existing drugs and has recently drawn attention and has led to several blockbuster drugs because of its high efficiency and low-cost. High-content screens, new biomarkers, noninvasive imaging techniques, and advanced in bioinformatics have created new opportunities for pursuing novel indications for approved compounds. Approved drugs all have known and well-characterized bioactivities, safety and bioavailability – properties which could dramatically accelerate drug development and optimization. Hits from this set will provide a significant head start in any drug optimization program. In addition, a growing number of compounds have been identified from this library that can functionally replace reprogramming transcription factors, enhance efficiency of iPSC generation and accelerate the reprogramming process by single use or a combination of several molecules.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1000

Approved Drug Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2860 approved drugs for high throughput screening (HTS) and high content screening (HCS);
  • All compounds collected in this library are drugs approved by Food and Drug Administration (FDA), the European Medicine Agency (EMA), or National Medical Products Administration (NMPA), etc;
  • An effective tool for discovering new with old drugs and new drug target identification;
  • Covers various research areas, such as Cancer, Cardiovascular disease, GPCR/G protein, Neuroscience, Membrane Transporter/Ion Channel, Microbiology & Virology, Immunology/Inflammation, Tyrosine Kinase/Adaptors, etc.
  • More detailed compound information with structure, target, activity, IC50 value, and brief introduction;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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Compound Library | TargetMol
Targetmol Compound Libraries
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Library Customization | TargetMol Library Composition

Antibacterial
Antibiotic
Autophagy
Apoptosis
Endogenous Metabolite
Adrenergic Receptor
5-HT Receptor
AChR
COX
Dopamine Receptor
Histamine Receptor
Parasite
Antifungal
HIV Protease
Sodium Channel
Potassium Channel
Calcium Channel
DNA/RNA Synthesis
Glucocorticoid Receptor
Estrogen/progestogen Receptor
Topoisomerase
SARS-CoV
PDE
Cytochromes P450
Ferroptosis
Influenza Virus
RAAS
EGFR
Reactive Oxygen Species
NF-κB
VEGFR
GABA Receptor
Dehydrogenase
c-Kit
HCV Protease
Mitophagy
Estrogen Receptor/ERR
PPAR
Serotonin Transporter
PDGFR
Nucleoside Antimetabolite/Analog
Cholinesterase (ChE)
Microtubule Associated
ribosome
Norepinephrine
Prostaglandin Receptor
Reverse Transcriptase
HSV
Proteasome
Progesterone Receptor
HBV
MAO
ATPase
Antifection
HDAC
Proton pump
Carbonic Anhydrase
iGluR
JAK
Androgen Receptor
FGFR
Src
DNA Alkylator/Crosslinker
Virus Protease
Bcr-Abl
FLT
ROS
DPP-4
Thrombin
Monoamine Oxidase
Adenosine Receptor
Tyrosine Kinases
TRP/TRPV Channel
Opioid Receptor
TNF
Thyroid hormone receptor(THR)
Transferase
c-Met/HGFR
MRP
HMG-CoA Reductase
HIF/HIF Prolyl-Hydroxylase
Phosphatase
PKC
NMDAR
PARP
Raf
IL Receptor
ALK
Amino Acids and Derivatives
Antifolate
CDK
Drug Metabolite
Mitochondrial Metabolism
MMP
GluR
Lipoxygenase
SGLT
Retinoid Receptor
AMPK
c-RET
DHFR
Interleukin
P-gp
HER
PI3K
Antioxidant
Factor Xa
DNA Alkylation
Endothelin Receptor
Antiviral
STAT
Phospholipase
NO Synthase
P2Y Receptor
ROCK
ABC Transporter
CaMK
mTOR
HSP
MEK
Tyrosinase
S1P Receptor
ADC Cytotoxin
Chloride channel
Histone Methyltransferase
NADPH
PKA
Serine Protease
P2X Receptor
DNA gyrase
Monoamine Transporter
TLR
Trk receptor
Nrf2
Beta Amyloid
HIF
DNA Methyltransferase
CFTR
Integrin
LPL Receptor
Reductase
Glutathione Peroxidase
GNRH Receptor
Cysteine Protease
FXR
Guanylate cyclase
Hedgehog/Smoothened
Vasopressin Receptor
DNA
Bcl-2 Family
Aromatase
GPR
Hydroxylase
Neurokinin receptor
Sigma receptor
TAM Receptor
ROS Kinase
Caspase
ERK
Fatty Acid Synthase
Xanthine Oxidase
Akt
PGE Synthase
NOS
p38 MAPK
Cell wall
GSK-3
Melatonin Receptor
Wnt/beta-catenin
Leukotriene Receptor
Aryl Hydrocarbon Receptor
Annexin A
UGT
MT Receptor
Molecular Glues
Smo
Isocitrate Dehydrogenase (IDH)
GPCR19
Decarboxylase
IκB/IKK
Neprilysin
Ligand for E3 Ligase
c-Fms
CGRP Receptor
Gap Junction Protein
Anti-infection
NOD
AhR
MicroRNA
Arginase
Histone Demethylase
CaSR
Serine/threonin kinase
LDL
Na-K-Cl cotransporter
Glucosidase
PAK
CCR
CXCR
IGF-1R
TGF-beta/Smad
Lipid
Free radical scavengers
Aminopeptidase
GST
Oxytocin Receptor
Adenosine Deaminase
Cannabinoid Receptor
Complement System
Syk
FAK
NOD-like Receptor (NLR)
Imidazoline Receptor
Vitamin
BTK
Monocarboxylate transporter
ROR
CRM1
Ligands for Target Protein for PROTAC
YAP
LTR
IFNAR
CETP
TOPK
Cholecystokinin Receptor
Rho
CSF-1R
IRE1
Gamma-secretase
GlyT
Integrase
Aurora Kinase
Thrombopoietin Receptor
Beta-Secretase
MAPK
Glutathione reductase
OAT
Acyltransferase
Ephrin Receptor
GluCls
RSV
Kras
GHSR
PLK
Ras
Protease-activated Receptor
Advanced Glycation End Products
Mdm2
Taste receptor
NPC1L1
RAR/RXR
Hydrogenase
DNA-PK
Dynamin
Na+/Ca2+ Exchanger
BACE
Lipase
JNK
gp120/CD4
VDA
Hck
Liver X Receptor
Immunology/Inflammation related
IAP
Myosin
Adiponectin Receptor
PAFR
MTH1
GRK
Glucagon Receptor
Phosphorylase
Hexokinase
PROTAC Linker
HCN Channel
FAAH
ACK1
Angiotensin-converting Enzyme (ACE)
Chk
Somatostatin
PAD
Epoxide Hydrolase
cAMP
Epigenetic Reader Domain
Mucin
DUB
Indoleamine 2,3-Dioxygenase (IDO)
Telomerase
ATP Citrate Lyase
STING
Sirtuin
CRFR
Pyroptosis
Melanocortin Receptor
CRISPR/Cas9
PDK
Aquaporin
Platelet aggregation
NADPH-oxidase
S6 Kinase
p53
PD-1/PD-L1
PKM