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TargetMol | Compound Library

Approved Drug Library

Catalog No. L1000

Traditional de novo drug discovery and development involves an HTS campaign for de novo candidate hits and requires highly specialized screening facilities and compound libraries containing several million compounds. It is a time consuming and expensive process. As the regulation for drug safety and efficacy is increasingly getting complex, the cost of developing new drugs is keeping skyrocket. Drug repositioning, also known as old drugs for new uses, is an effective strategy to find new indications for existing drugs and has recently drawn attention and has led to several blockbuster drugs because of its high efficiency and low-cost. High-content screens, new biomarkers, noninvasive imaging techniques, and advanced in bioinformatics have created new opportunities for pursuing novel indications for approved compounds. Approved drugs all have known and well-characterized bioactivities, safety and bioavailability – properties which could dramatically accelerate drug development and optimization. Hits from this set will provide a significant head start in any drug optimization program. In addition, a growing number of compounds have been identified from this library that can functionally replace reprogramming transcription factors, enhance efficiency of iPSC generation and accelerate the reprogramming process by single use or a combination of several molecules.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1000

Approved Drug Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2860 approved drugs for high throughput screening (HTS) and high content screening (HCS);
  • All compounds collected in this library are drugs approved by Food and Drug Administration (FDA), the European Medicine Agency (EMA), or National Medical Products Administration (NMPA), etc;
  • An effective tool for discovering new with old drugs and new drug target identification;
  • Covers various research areas, such as Cancer, Cardiovascular disease, GPCR/G protein, Neuroscience, Membrane Transporter/Ion Channel, Microbiology & Virology, Immunology/Inflammation, Tyrosine Kinase/Adaptors, etc.
  • More detailed compound information with structure, target, activity, IC50 value, and brief introduction;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

Antibacterial
Antibiotic
Autophagy
Apoptosis
Endogenous Metabolite
5-HT Receptor
Adrenergic Receptor
AChR
COX
Dopamine Receptor
Histamine Receptor
Parasite
Antifungal
HIV Protease
Sodium Channel
Potassium Channel
Calcium Channel
DNA/RNA Synthesis
Glucocorticoid Receptor
Topoisomerase
Estrogen/progestogen Receptor
SARS-CoV
PDE
Ferroptosis
Cytochromes P450
RAAS
Influenza Virus
EGFR
Reactive Oxygen Species
NF-κB
GABA Receptor
VEGFR
Dehydrogenase
Mitophagy
PPAR
c-Kit
HCV Protease
Estrogen Receptor/ERR
Serotonin Transporter
PDGFR
Nucleoside Antimetabolite/Analog
Cholinesterase (ChE)
ribosome
Microtubule Associated
Reverse Transcriptase
HSV
Norepinephrine
Prostaglandin Receptor
Progesterone Receptor
Proteasome
MAO
HBV
ATPase
iGluR
Antifection
HDAC
Carbonic Anhydrase
Proton pump
JAK
Androgen Receptor
FGFR
Src
Virus Protease
Bcr-Abl
FLT
DNA Alkylator/Crosslinker
ROS
Opioid Receptor
DPP-4
Thrombin
Monoamine Oxidase
c-Met/HGFR
Adenosine Receptor
TRP/TRPV Channel
Tyrosine Kinases
TNF
Phosphatase
Thyroid hormone receptor(THR)
Transferase
NMDAR
MRP
PKC
HMG-CoA Reductase
PARP
Raf
Drug Metabolite
IL Receptor
MMP
ALK
HIF/HIF Prolyl-Hydroxylase
Amino Acids and Derivatives
GNRH Receptor
Antifolate
Mitochondrial Metabolism
CDK
GluR
SGLT
Retinoid Receptor
DHFR
Lipoxygenase
Interleukin
P-gp
AMPK
Phospholipase
c-RET
PI3K
Antioxidant
Factor Xa
DNA Alkylation
CaMK
Antiviral
NO Synthase
HER
P2Y Receptor
Serine Protease
ROCK
DNA gyrase
ABC Transporter
Endothelin Receptor
mTOR
STAT
Tyrosinase
S1P Receptor
ADC Cytotoxin
Chloride channel
Histone Methyltransferase
Reductase
NADPH
PKA
P2X Receptor
Monoamine Transporter
Guanylate cyclase
Vasopressin Receptor
HSP
TLR
Trk receptor
MEK
CFTR
Nrf2
Neurokinin receptor
DNA Methyltransferase
LPL Receptor
Glutathione Peroxidase
Integrin
Cysteine Protease
FXR
Bcl-2 Family
Hedgehog/Smoothened
Beta Amyloid
Aromatase
GPR
Hydroxylase
Sigma receptor
TAM Receptor
ROS Kinase
Caspase
ERK
Fatty Acid Synthase
Xanthine Oxidase
DNA
Akt
HIF
Cell wall
GSK-3
Melatonin Receptor
p38 MAPK
CaSR
Wnt/beta-catenin
Annexin A
UGT
Cholecystokinin Receptor
Leukotriene Receptor
Aryl Hydrocarbon Receptor
MT Receptor
Smo
PGE Synthase
GPCR19
Decarboxylase
Molecular Glues
Isocitrate Dehydrogenase (IDH)
IκB/IKK
Neprilysin
AhR
Ligand for E3 Ligase
Oxytocin Receptor
Anti-infection
NOD
NOS
Arginase
MicroRNA
Histone Demethylase
Serine/threonin kinase
LDL
Gamma-secretase
Na-K-Cl cotransporter
Glucosidase
CXCR
TGF-beta/Smad
Free radical scavengers
PAK
CCR
IGF-1R
Lipid
Aminopeptidase
GST
c-Fms
CGRP Receptor
Melanocortin Receptor
Adenosine Deaminase
Cannabinoid Receptor
Complement System
Gap Junction Protein
Syk
FAK
NOD-like Receptor (NLR)
Imidazoline Receptor
Vitamin
BTK
Monocarboxylate transporter
ROR
CRM1
TOPK
Ligands for Target Protein for PROTAC
YAP
LTR
IFNAR
CETP
IRE1
Rho
GlyT
Hexokinase
Somatostatin
Aurora Kinase
Thrombopoietin Receptor
Beta-Secretase
Glutathione reductase
Acyltransferase
Integrase
MAPK
OAT
Ephrin Receptor
GluCls
Protease-activated Receptor
RSV
Kras
GHSR
PLK
Ras
Taste receptor
DNA-PK
Dynamin
BACE
JNK
gp120/CD4
Advanced Glycation End Products
Mdm2
NPC1L1
RAR/RXR
Hydrogenase
Na+/Ca2+ Exchanger
Lipase
VDA
IAP
Myosin
Adiponectin Receptor
Phosphorylase
Hck
Liver X Receptor
CSF-1R
Immunology/Inflammation related
PAFR
GRK
Glucagon Receptor
HCN Channel
ACK1
Bradykinin Receptor
Angiotensin-converting Enzyme (ACE)
Chk
cAMP
Epigenetic Reader Domain
Mucin
DUB
ATP Citrate Lyase
STING
Sirtuin
PROTAC Linker
FAAH
PAD
Epoxide Hydrolase
Indoleamine 2,3-Dioxygenase (IDO)
Telomerase
Pyroptosis
PDK
PKM
CRISPR/Cas9
Aquaporin
Platelet aggregation
NADPH-oxidase
S6 Kinase
p53
PD-1/PD-L1