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Anti-PMS2 Antibody (2B500)

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Catalog No. TMAC-03386

Anti-PMS2 Antibody (2B500) is a Rabbit antibody targeting PMS2. Anti-PMS2 Antibody (2B500) can be used in WB,ICC/IF,IHC,IP,FCM.

Anti-PMS2 Antibody (2B500)

Anti-PMS2 Antibody (2B500)

😃Good
Catalog No. TMAC-03386
Anti-PMS2 Antibody (2B500) is a Rabbit antibody targeting PMS2. Anti-PMS2 Antibody (2B500) can be used in WB,ICC/IF,IHC,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-PMS2 Antibody (2B500) is a Rabbit antibody targeting PMS2. Anti-PMS2 Antibody (2B500) can be used in WB,ICC/IF,IHC,IP,FCM.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-100; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression. Two additional homologs of the prokaryotic MutL gene, designated PMS1 and PMS2, have been identified and shown to be mutated in the germline of HNPCC patients.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 96 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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