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4-Hydroxyphenylbutazone

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Catalog No. T39152Cas No. 16860-43-8

4-Hydroxyphenylbutazone, a metabolite of Phenylbutazone, functions as an effective reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone is a nonsteroidal anti-inflammatory drug (NSAID) known for its efficiency in this role.

4-Hydroxyphenylbutazone

4-Hydroxyphenylbutazone

😃Good
Catalog No. T39152Cas No. 16860-43-8
4-Hydroxyphenylbutazone, a metabolite of Phenylbutazone, functions as an effective reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone is a nonsteroidal anti-inflammatory drug (NSAID) known for its efficiency in this role.
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Product Introduction

Bioactivity
Description
4-Hydroxyphenylbutazone, a metabolite of Phenylbutazone, functions as an effective reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone is a nonsteroidal anti-inflammatory drug (NSAID) known for its efficiency in this role.
In vitro
4-Hydroxyphenylbutazone is derived from phenylbutazone through incubation with either ram seminal vesicle microsomes or horseradish peroxidase. It is an ineffective inhibitor of PHS (cyclooxygenase)[1].
Chemical Properties
Molecular Weight324.38
FormulaC19H20N2O3
Cas No.16860-43-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

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