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Pratol

Name: Pratol
Brand: TargetMol
SKU: TN3231
Price: 82 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TN3231Cas No. 487-24-1

Alias 7-Hydroxy-4'-methoxyflavone

Pratol (7-Hydroxy-4'-methoxyflavone) significantly increased melanin content and tyrosinase activity in the cells without being cytotoxic.

Pratol

🥰Excellent

Purity: 99.06%

Catalog No. TN3231Alias 7-Hydroxy-4'-methoxyflavoneCas No. 487-24-1

Pratol (7-Hydroxy-4'-methoxyflavone) significantly increased melanin content and tyrosinase activity in the cells without being cytotoxic.

Pack Size	Price	Availability
1 mg	$82	In Stock
5 mg	$248	In Stock
10 mg	$364	In Stock
25 mg	$645	In Stock
1 mL x 10 mM (in DMSO)	$278	In Stock

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Batch Information

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Purity:99.06%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Pratol (7-Hydroxy-4'-methoxyflavone) significantly increased melanin content and tyrosinase activity in the cells without being cytotoxic.
Synonyms	7-Hydroxy-4'-methoxyflavone

Chemical Properties

Molecular Weight	268.26
Formula	C₁₆H₁₂O₄
Cas No.	487-24-1
Smiles	O=C1C=2C(OC(=C1)C3=CC=C(OC)C=C3)=CC(O)=CC2
Relative Density.	1.329 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (242.3 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7277 mL	18.6386 mL	37.2773 mL	186.3863 mL
5 mM	0.7455 mL	3.7277 mL	7.4555 mL	37.2773 mL
10 mM	0.3728 mL	1.8639 mL	3.7277 mL	18.6386 mL
20 mM	0.1864 mL	0.9319 mL	1.8639 mL	9.3193 mL
50 mM	0.0746 mL	0.3728 mL	0.7455 mL	3.7277 mL
100 mM	0.0373 mL	0.1864 mL	0.3728 mL	1.8639 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc