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Anti-Securin Antibody (7P480)
(Synonyms: TUTR1, TUTR 1, Tumor-transforming protein 1, Tumor transforming protein 1, Tumor transforming 1, Securin, Pttg3, PTTG1_HUMAN, PTTG1 protein, PTTG1, PTTG 1, PTTG, Pituitary tumor-transforming gene 1 protein, Pituitary tumor-transforming gene 1, Pituitary tumor-transforming 1, isoform CRA_b, Pituitary tumor-transforming 1, isoform CRA_a, Pituitary tumor transforming protein 1, Pituitary tumor transforming 1, Pds1, MGC138276, MGC126883, hPTTG, Esp1-associated protein, ESP1 associated protein 1, EAP1, EAP 1, Cut2, C87862, AW555095) Copy Product Info
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Synonyms: TUTR1, TUTR 1, Tumor-transforming protein 1, Tumor transforming protein 1, Tumor transforming 1, Securin, Pttg3, PTTG1_HUMAN, PTTG1 protein, PTTG1, PTTG 1, PTTG, Pituitary tumor-transforming gene 1 protein, Pituitary tumor-transforming gene 1, Pituitary tumor-transforming 1, isoform CRA_b, Pituitary tumor-transforming 1, isoform CRA_a, Pituitary tumor transforming protein 1, Pituitary tumor transforming 1, Pds1, MGC138276, MGC126883, hPTTG, Esp1-associated protein, ESP1 associated protein 1, EAP1, EAP 1, Cut2, C87862, AW555095
Catalog No. TMAC-03701 Copy Product Info
🥰Excellent
Anti-Securin Antibody (7P480) is a Rabbit antibody targeting Securin. Anti-Securin Antibody (7P480) can be used in FCM,ICC,IF,IHC,IP,WB.
Anti-Securin Antibody
(7P480)
(7P480)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Securin Antibody (7P480) is a Rabbit antibody targeting Securin. Anti-Securin Antibody (7P480) can be used in FCM,ICC,IF,IHC,IP,WB. |
| Synonyms | TUTR1, TUTR 1, Tumor-transforming protein 1, Tumor transforming protein 1, Tumor transforming 1, Securin, Pttg3, PTTG1_HUMAN, PTTG1 protein, PTTG1, PTTG 1, PTTG, Pituitary tumor-transforming gene 1 protein, Pituitary tumor-transforming gene 1, Pituitary tumor-transforming 1, isoform CRA_b, Pituitary tumor-transforming 1, isoform CRA_a, Pituitary tumor transforming protein 1, Pituitary tumor transforming 1, Pds1, MGC138276, MGC126883, hPTTG, Esp1-associated protein, ESP1 associated protein 1, EAP1, EAP 1, Cut2, C87862, AW555095 |
| Ig Type | IgG |
| Clone | 7P480 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The product of the oncogene PTTG, pituitary tumor transforming gene, is a human homolog of the anaphase-inhibitor vertebrate protein, securin. PTTG contains a basic amino-terminal domain and an acidic carboxy-terminal domain, which acts as a transactivation domain when fused to a heterologous DNA binding domain. Human PTTG is overexpressed in Jurkat and is also detected in human thymus, testis and placenta. PTTG is mainly expressed in the cytoplasm and is also partially localized to the nucleus. Vertebrate PTTG regulates the separin Esp1, which promotes chromatid separation, to overcome the cohesive forces that hold sister chromatids together. This regulatory function of PTTG suggests that defective regulation of cohesion may contribute to cancer by promoting chromosome instability. Although vertebrate PTTG shares cell-cycle functions with its yeast securin counterparts Pds1p and Cut2, none share sequence homology. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 22 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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