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Anti-SCXA Polyclonal Antibody

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Catalog No. TMAB-01670
Alias SCXB, SCX, scleraxis homolog A, Class A basic helix-loop-helix protein 48, Class A basic helix-loop-helix protein 41, bHLHa48, bHLHa41, Basic helix-loop-helix transcription factor scleraxis

Anti-SCXA Polyclonal Antibody is a Rabbit antibody targeting SCXA. Anti-SCXA Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-SCXA Polyclonal Antibody

Anti-SCXA Polyclonal Antibody

😃Good
Catalog No. TMAB-01670Alias SCXB, SCX, scleraxis homolog A, Class A basic helix-loop-helix protein 48, Class A basic helix-loop-helix protein 41, bHLHa48, bHLHa41, Basic helix-loop-helix transcription factor scleraxis
Anti-SCXA Polyclonal Antibody is a Rabbit antibody targeting SCXA. Anti-SCXA Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceAvailabilityQuantity
50 μL$2217-10 days
100 μL$3747-10 days
200 μL$5297-10 days
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Product Introduction

Bioactivity
Description
Anti-SCXA Polyclonal Antibody is a Rabbit antibody targeting SCXA. Anti-SCXA Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
AliasSCXB, SCX, scleraxis homolog A, Class A basic helix-loop-helix protein 48, Class A basic helix-loop-helix protein 41, bHLHa48, bHLHa41, Basic helix-loop-helix transcription factor scleraxis
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Chicken,Dog,Cow,Horse)
Verified Activity
Tissue/cell: rat thyroid gland; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-SCXA Polyclonal Antibody, Unconjugated (TMAB-01670) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
Application
IHC-P,IHC-Fr,IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundTranscription factors are proteins that bind DNA adjacent to genes and control the production of mRNA transcripts. Scleraxis (basic helix-loop-helix transcription factor scleraxis) is a 201 amino acid protein that dimerizes with another bHLH protein to initiate transcription. Scleraxis is known to play a role in formation of mesoderm and somite-derived chondrogenic lineages. Scleraxis localizes to the nucleus and contains 1 bHLH domain. bHLH transcription factors, in general, function in cellular differentiation, proliferation, and oncogene regulation. The gene encoding Scleraxis maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SCXA
Antigen Species
Human
Gene ID
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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