PIGR Protein, Human, Recombinant (S365G, His)

PIGR Protein, Human, Recombinant (S365G, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69 kDa and the accession number is P01833.

Pack Size	Availability	Price/USD	Quantity
100 μg	5 days	$ 600.00
1 mg	5 days	$ 3,910.00

Pack Size

Availability

Price/USD

Quantity

100 μg

5 days

$ 600.00

1 mg

5 days

$ 3,910.00

Description

PIGR Protein, Human, Recombinant (S365G, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69 kDa and the accession number is P01833.

Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	P01833
Synonyms	PIGR, FLJ22667, polymeric immunoglobulin receptor, MGC125362, MGC125361
Construction	extracellular domain (Met 1-Arg 638, 365 Ser/Gly) of Human PIGR (NP_002635.2)
Protein Purity	> 97 % as determined by SDS-PAGE
Molecular Weight	69 kDa (predicted)

Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.