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Ephrin A1/EFNA1 Protein, Mouse, Recombinant (His)

(Synonyms: Lerk1, Eplg1, Epl1, ephrin-A1, Efl1, B61, AI325262) Copy Product Info

Synonyms: Lerk1, Eplg1, Epl1, ephrin-A1, Efl1, B61, AI325262

Catalog No. TMPY-01723 Copy Product Info
Ephrin A1/EFNA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is P52793.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$557-10 days7-10 days
10 µg$877-10 days7-10 days
20 µg$1427-10 days7-10 days
50 µg$2777-10 days7-10 days
100 µg$5357-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Information

Bioactivity
Bioactivity
Measured by its ability to compete with mouse EFNA1 for binding to immobilized mouse EphA2 in a functional ELISA assay.
Description
Ephrin A1/EFNA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is P52793.
Species
Mouse
Expression System
HEK293 Cells
TagC-His
Accession NumberP52793
ConstructionA DNA sequence encoding the mouse EFNA1 (NP_034237.3) without the pro peptide (Met 1-Ser 182) was fused with a polyhistidine tag at the C-terminus. Predicted N terminal: Asp 19
Protein Purity
> 97 % as determined by SDS-PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsLerk1, Eplg1, Epl1, ephrin-A1, Efl1, B61, AI325262
Research Background
EPH-related receptor tyrosine kinase ligand 1 (abbreviated as Ephrin-A1) also known as ligand of eph-related kinase 1 or EFNA1, is a member of the ephrin (EPH) family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A1/EFNA1 and its Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. Ephrin-A1 and one of its receptor EphA2 were expressed in xenograft endothelial cells and also tumor cells and play a role in human cancers, at least in part by influencing tumor neovascularization.
Chemical Properties
Molecular Weight20 kDa (predicted); 27 kDa (reducing condition, due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: Ephrin A1/EFNA1 Protein, Mouse, Recombinant (His) chemical structure | Ephrin A1/EFNA1 Protein, Mouse, Recombinant (His) molecular weight