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Anti-CLEC4E Polyclonal Antibody
(Synonyms: MINCLE, Macrophage-Inducible C-Type Lectin, C-Type Lectin Superfamily Member 9, C-Type Lectin Domain Family 4 Member E, CLECSF9, CLEC4E) Copy Product Info
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Synonyms: MINCLE, Macrophage-Inducible C-Type Lectin, C-Type Lectin Superfamily Member 9, C-Type Lectin Domain Family 4 Member E, CLECSF9, CLEC4E
Catalog No. TMAB-00446 Copy Product Info
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Anti-CLEC4E Polyclonal Antibody is a Rabbit antibody targeting CLEC4E. Anti-CLEC4E Polyclonal Antibody can be used in FCM.
Anti-CLEC4E Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-CLEC4E Polyclonal Antibody is a Rabbit antibody targeting CLEC4E. Anti-CLEC4E Polyclonal Antibody can be used in FCM. |
| Synonyms | MINCLE, Macrophage-Inducible C-Type Lectin, C-Type Lectin Superfamily Member 9, C-Type Lectin Domain Family 4 Member E, CLECSF9, CLEC4E |
| Ig Type | IgG |
| Reactivity | Human (predicted:Horse,Cow,Rat,Mouse) |
| Application | |
| Recommended Dose | FCM: 2μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B. |
| Immunogen | KLH conjugated synthetic peptide: human CLECSF9 |
| Antigen Species | Human |
| Gene Name | CLEC4E |
| Gene ID | |
| Protein Name | C-type lectin domain family 4 member E |
| Uniprot ID | |
| Biology Area | Macrophage / Inflamm. |
| Function | C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B |
| Molecular Weight | Theoretical: 25 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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