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Anti-GM-CSFR alpha Antibody-PE (5Q649)
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Catalog No. TMAY-01090P
Anti-GM-CSFR alpha Antibody-PE (5Q649) is a PE-conjugated Mouse antibody targeting GM-CSFR alpha. Anti-GM-CSFR alpha Antibody-PE (5Q649) can be used in FCM.
Anti-GM-CSFR alpha Antibody-PE (5Q649)
Anti-GM-CSFR alpha Antibody-PE (5Q649)
🥰Excellent
Catalog No. TMAY-01090P
Anti-GM-CSFR alpha Antibody-PE (5Q649) is a PE-conjugated Mouse antibody targeting GM-CSFR alpha. Anti-GM-CSFR alpha Antibody-PE (5Q649) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-GM-CSFR alpha Antibody-PE (5Q649) is a PE-conjugated Mouse antibody targeting GM-CSFR alpha. Anti-GM-CSFR alpha Antibody-PE (5Q649) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5Q649 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of anti-human GM-CSFRa(CD116) on human whole blood monocytes. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable monocytes. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD116 / GM-CSFR (rh CD116 / GM-CSFR; TMPY-01065; P15509-1; Met1-Gly320) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | CD116/GM-CSFR has been preferentially associated with M4, M5 subtype of AML but is not specific. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Physiologically, CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell. A signal cascade is usually initiated, altering the behavior of the cell (see cell signaling). Some CD proteins do not play a role in cell signaling, but have other functions, such as cell adhesion. CD116/GM-CSFR is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. CD116/GM-CSFR is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. |
| Conjucates | PE |
| Immunogen | Recombinant Human CD116 / GM-CSFR protein (TMPY-01065) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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